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Leancare Ltd.
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| | Dibrompropamidine Basic information |
| Product Name: | Dibrompropamidine | | Synonyms: | 4,4'-(Trimethylenedioxy)bis(3-bromobenzamidine);Dibrompropamidine;4,4'-(Trimethylenebisoxy)bis(3-bromobenzamidine);4,4'-[1,3-Propanediylbis(oxy)]bis(3-bromobenzamidine);4,4'-[1,3-Propanediylbisoxy]bis(3-bromobenzamidine);Benzenecarboximidamide, 4,4'-[1,3-propanediylbis(oxy)]bis[3-bromo- | | CAS: | 496-00-4 | | MF: | C17H18Br2N4O2 | | MW: | 470.16 | | EINECS: | | | Product Categories: | | | Mol File: | 496-00-4.mol |  |
| | Dibrompropamidine Chemical Properties |
| | Dibrompropamidine Usage And Synthesis |
| Originator | Dibrompropamidine,Aventis Pharma AS | | Definition | ChEBI: Dibrompropamidine is an aromatic ether. | | Manufacturing Process | 2,2’-Dibromo-4,4’-dicyano-α,γ-diphenoxypropane (3.0 g) and anhydrous
ethanol (3.0 ml) were dissolved in anhydrous chloroform (40 ml). The solution
was saturated at 0°C with dry hydrogen chloride and set aside for 7 day. The
iminoether hydrochloride which crystallised out, was filtered off and washed
with light petroleum. The solid was added to 12% ammoniacal ethanol (47
c.c.) and the mixture was heated at 60°C for 6 hours. Solution was obtained
after 3 hours and the amidine hydrochloride began to cryistallise. The mixture
was ice-cooled, and the white crystalline solid was filtered off, washed with 2
N hydrochloric acid, and recrystallised twice from 0.5 N hydrochloric acid.
2,2'-Dibromo-4,4'-diamidino-α,γ-diphenoxypropane dihydrochloride (2.1 g)
[another name: 4,4'-(Trimethylenedioxy)bis(3-bromobenzamidine)] separated
as white prisme. Melting point 309°C. (decomp.).
Berg S.S., GB Patent No. 598,911; March 22, 1945; Assigned to May and
Bakker Limited, a British Co., Dagenham, Essecs. | | Therapeutic Function | Antiprotozoal |
| | Dibrompropamidine Preparation Products And Raw materials |
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