| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
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jkinfo@jkchemical.com |
| Products Intro: |
Product Name:SucciniMidyl 6-[3-(2-Pyridyldithio)propionaMido]hexanoate
CAS:158913-22-5
Package:250Mg,25Mg
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Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate manufacturers
- SPDP-C6-NHS ester
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- $31.00 / 2mg
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2024-10-24
- CAS:158913-22-5
- Min. Order:
- Purity:
- Supply Ability: 10g
- SPDP-C6-NHS ester
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- $0.00 / 50mg
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2024-03-21
- CAS:158913-22-5
- Min. Order: 50mg
- Purity: >99.00%
- Supply Ability: 50mg
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| | Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate Basic information |
| | Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate Chemical Properties |
| Melting point | 82-84°C | | density | 1.36±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: 100 mg/mL (235.01 mM) | | pka | 15.67±0.46(Predicted) | | form | Solid | | color | White |
| | Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate Usage And Synthesis |
| Description | SPDP-C6-NHS ester contains a disulfide bond which is cleavable upon reduction. The NHS ester is reactive toward primary amine and sulfhydryl groups. SPDP-C6-NHS ester is commonly used for bioconjugation and reversible crosslinkings. | | Chemical Properties | White Solid | | Uses | A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. | | General Description | The amine-reactive portion of SPDP reagents is the N-hydroxysuccinimide (NHS) ester. Reactions are most commonly performed in phosphate, carbonate/bicarbonate, or borate buffers at pH 7-8. Other buffers can be used provided they do not contain primary amines (or thiols or disulfide reducing reagents – see discussion of the sulfhydryl reactivity). The rate of reaction and degradation by hydrolysis increases with increasing pH; for example, the half-life of the NHS ester is several hours at pH 7 and less than 10 minutes at pH 9. NHS-ester reagents like SPDP and LC-SPDP have limited aqueous solubility and must be dissolved in organic solvent before adding them to a reaction mixture. Sulfo-NHS-ester reagents like Sulfo-LC-SPDP are water-soluble and can be added directly to aqueous reaction mixtures. |
| | Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate Preparation Products And Raw materials |
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