| Company Name: |
J & K SCIENTIFIC LTD.
|
| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Tixocortol
CAS:61951-99-3
Package:500Mg,50Mg
|
| Company Name: |
Chemsky (shanghai) International Co.,Ltd
|
| Tel: |
021-50135380 |
| Email: |
shchemsky@sina.com |
| Products Intro: |
Product Name:Tixocortol;(11β)-11,17-Dihydroxy-21-Mercaptopregn-4-ene-3,20-dione; 11β,17-Dihydroxy-21-Mercaptoprogesterone; Cortisol 21-Thiol
CAS:61951-99-3
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:Tixocortol
CAS:61951-99-3
Purity:NULL Package:100mg;10mg;25mg;500mg;50mg;5mg Remarks:NULL
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| | Tixocortol Basic information |
| | Tixocortol Chemical Properties |
| | Tixocortol Usage And Synthesis |
| Originator | Pivalone,Jouveinal,France,1978 | | Uses | Tixocortol is an anti-inflammatory agent. Tixocortol is used in fluorescent chemoaffinity labeling. | | Definition | ChEBI: A steroid sulfide in which the sulfanyl group is at C-21 of a polyoxygenated derivative of pregn-4-ene. | | Manufacturing Process | In a reactor of 50 liters, sodium S-thiopivalate is prepared from 100 g of S_x0002_thiopivalic acid (0.844 mol), 214 cc of solution of sodium methylate, 3.95 M
(0.844 mol) in 25 liters of anhydrous acetone.
There are then added 285 g (0.603 mol) of dihydroxy-11β,17α-iodo-21-dioxo-
3,20-pregnene-4 and the mixture is brought up to the acetone reflux for two
hours. The solvent is eliminated by distillation under vacuum until there is
obtained a syrupy residue which is poured into 10 liters of iced water. The
insoluble part is filtered and dried under vacuum.
The crude product is purified by recrystallization from ethanol; weight: 250 g;
yield: 89.5%. | | Therapeutic Function | Antiinflammatory |
| | Tixocortol Preparation Products And Raw materials |
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