|
|
| | Flucycloxuron Basic information |
| Product Name: | Flucycloxuron | | Synonyms: | Flucycloxuron;A 1335;Benzamide, N-(((4-(((((4-chlorophenyl)cyclopropylmethylene)amino)oxy)methyl)phenyl)amino)carbonyl)-2,6-difluoro-;Flucycloxuron [iso];N-[[4-[[[(4-chlorophenyl)-cyclopropyl-methylidene]amino]oxymethyl]phen yl]carbamoyl]-2,6-difluoro-benzamide;benzamide, n-(((4-(((((4-chlorophenyl)cyclopropylmethylene)amino)oxy)methyl)phe;1-[α-(4-chloro-α-cyclopropylbenzylideneaminooxy)-p-tolyl]-3-(2,6-difluorobenzoyl)urea;FlucycloxuronSolution,100mg/L,5x1ml | | CAS: | 113036-88-7 | | MF: | C25H20ClF2N3O3 | | MW: | 483.89 | | EINECS: | | | Product Categories: | | | Mol File: | 113036-88-7.mol |  |
| | Flucycloxuron Chemical Properties |
| RIDADR | 3077 | | WGK Germany | 3 | | HazardClass | 9 | | PackingGroup | III |
| | Flucycloxuron Usage And Synthesis |
| Description | Flucycloxuron is a chitin synthesis inhibitor and a mite growth regulator, active against pest egg and larval stages, on a variety of crops.Trade names include Andalin. | | Chemical Properties | Flucycloxuron is a benzoylurea acaricide and an insect growth regulator. It exists as off-white to yellow crystals, insoluble in water, sparingly soluble in cyclohexane，xylene，ethanol and soluble in N-methylpyrrolidone. | | Uses | Flucycloxuron is benzoylurea based insecticide that is a chitin synthesis inhibitor. | | Definition | ChEBI: Flucycloxuron is a benzoylurea insecticide, a member of monochlorobenzenes, a member of phenylureas, a difluorobenzene and a member of cyclopropanes. It has a role as a mite growth regulator. | | Preparation | Flucycloxuron is produced by the reaction of 4-chlorocyclopropylphenone with hydroxylamine to yield the corresponding oxime, which is treated with 4-nitrobenzylbromide,followed by reduction to give the corresponding amine that is fur-ther treated with 2,6-difluorobenzoylisocyanate. | | Toxicology | The WHO classifies flucycloxuron as a Class U toxin(unlikely to be hazardous). It is non-irritating to skin but mildly irritating to eyes. It is non-mutagenic, non-teratogenic and non-carcinogenic. The acute oral LD50, in rats is >5000 mg/kg.The acute dermal LD50 in rats is >2000 mg/kg.The NOEL inrats (2 year feed) is about 6 mg/kg/day. | | Mode of action | Incorporation of N-acetylglucosamine into chitin was equally inhibited by flucycloxuron and diflubenzuron. Flucycloxuron has ovo-Iarvicidal activity (Grosscurt et al. 1988). Ir is non-systemic and has no activity on adults (Tomlin 1995). |
| | Flucycloxuron Preparation Products And Raw materials |
|