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| | 18-(tert-Butoxy)-18-oxooctadecanoic Acid Basic information | | Appearance |
| Product Name: | 18-(tert-Butoxy)-18-oxooctadecanoic Acid | | Synonyms: | OCTADECANEDIOIC ACID MONO-TERT-BUTYL ESTER;18-(tert-Butoxy);-18-oxooctadecanoic acid;Octadecanedioic acid,1-(1,1-dimethylethyl) ester;18-[(2-methylpropan-2-yl)oxy]-18-oxooctadecanoic acid;tert-butyl 17-carboxyheptadecanoate;mono-t-Butyl stearate;tert-Butyl Hydrogen Octadecanedioate | | CAS: | 843666-40-0 | | MF: | C22H42O4 | | MW: | 370.57 | | EINECS: | | | Product Categories: | 843666-40-0 | | Mol File: | 843666-40-0.mol |  |
| | 18-(tert-Butoxy)-18-oxooctadecanoic Acid Chemical Properties |
| Melting point | 68 °C | | Boiling point | 470.7±18.0 °C(Predicted) | | density | 0.950±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 4.78±0.10(Predicted) | | form | Solid | | color | White to Off-White |
| | 18-(tert-Butoxy)-18-oxooctadecanoic Acid Usage And Synthesis |
| Appearance | White to Almost white powder to crystal | | Description | Octadecanedioic acid mono-tert-butyl ester is a non-cleavable ADC linker or alkyl chain-based PROTAC linker for the synthesis of antibody-drug couplings (ADCs) and PROTACs. | | Uses | 18-(tert-Butoxy)-18-oxooctadecanoic Acid is used to engineer long-acting, potent exendin-4 based GLP-1 analog for microstructure-based transdermal delivery for glycemic control. | | Application | 18-(tert-Butoxy)-18-oxooctadecanoic acid) is a short linker featuring a carboxylic acid and a tert-butyl ester. Carboxylic acids can be reacted with alcohols or amines, while the tert-butyl ester can be deprotected and further connected to another molecule. It is a pharmaceutical intermediate ingredient used in the preparation of somatostatin. It also has catalytic activity. |
| | 18-(tert-Butoxy)-18-oxooctadecanoic Acid Preparation Products And Raw materials |
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