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Shanghai EFE Biological Technology Co., Ltd.
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Product Name:11β-13,14-dihydro-15-keto Prostaglandin F2α
CAS:107615-77-0
Purity:95% Package:50μg;100μg;500μg
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Shanghai Hongye Biotechnology Co. Ltd
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400-9205774 |
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sales@glpbio.cn |
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Product Name:11β-13,14-dihydro-15-keto Prostaglandin F2α
CAS:107615-77-0
Purity:>98% Package:1mg;10mg;50mg;100mg;
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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Product Name:11β-13,14-dihydro-15-keto Prostaglandin F2α
CAS:107615-77-0
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
TargetMol Chemicals Inc.
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15002134094 |
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marketing@targetmol.cn |
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Product Name:11β-13,14-dihydro-15-keto Prostaglandin F2α
CAS:107615-77-0
Package:10mg;50mg
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|
| | 11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA Basic information |
| | 11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA Chemical Properties |
| solubility | 10 mM Na2CO3: >6.5 mg/ml (from PGF2a); DMF: >100 mg/ml (from PGF2a); DMSO: >100 mg/ml (from PGF2a); Ethanol: >100 mg/ml (from PGF2a); PBS pH 7.2: >10 mg/ml (from PGF2a) |
| | 11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA Usage And Synthesis |
| Description | 11β-13,14-dihydro-15-keto PGF2α is a metabolite of PGD2 in the 15-hydroxy PGDH pathway.1,2 Infusion or inhalation of tritiated PGD2 in normal males results in the appearance of peak levels of both 11β-PGF2α, as the immediate product, and 11β-13,14-dihydro-15-keto PGF2α in the plasma within 10 minutes.1 Homogenates of human lung metabolize PGD2 first to 11β-PGF2α and then to 11β-15-keto-PGF2α in the presence of NAD+, but not 11β-13,14-dihydro-15-keto PGF2α.2 Guinea pig liver and kidney homogenates metabolize PGD2 to 11β-13,14-dihydro-15-keto PGF2α, via 11β-PGF2α, in the presence of NAD+ and NADP+.2 | | Uses | 11β-13,14-Dihydro-15-keto Prostaglandin F2α is the deviative of 13,14-Dihydro-15-keto PGF2a (HY-113208), which is an endogenous metabolite present in Blood that can be used for the research of Pregnancy[1][2]. | | Definition | ChEBI: 11beta-13,14-dihydro-15-keto-PGF2alpha is a prostanoid. | | References | 1. Robinson, C., Hardy, C.C., and Holgate, S.T. The metabolism of prostaglandin D2 after inhalation or intravenous infusion in normal men Biochim. Biophys. Acta 963(2),151-161(1988).
2. Robinson, C., Herbert, C.A., Bedwell, S., et al. The metabolism of prostaglandin D2. Evidence for the sequential conversion by NADPH and NAD+ dependent pathways Biochem. Pharmacol. 38(19),3267-3271(1989). |
| | 11BETA-13, 14-DIHYDRO-15-KETO PROSTAGLANDIN F2ALPHA Preparation Products And Raw materials |
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