| CODEINE HYDROCHLORIDE Basic information |
Product Name: | CODEINE HYDROCHLORIDE | Synonyms: | CODEINE HYDROCHLORIDE DIHYDRATE;Codeinum Hcl;(4R,4aR,7S,7aR,12bS)-9-Methoxy-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol hydrochloride;NUXLENPAZQNFAM-FFHNEAJVSA-N | CAS: | 1422-07-7 | MF: | C18H22ClNO3 | MW: | 335.83 | EINECS: | 215-829-5 | Product Categories: | | Mol File: | 1422-07-7.mol | |
| CODEINE HYDROCHLORIDE Chemical Properties |
Melting point | ~280° with some decompn | alpha | D22 -108° | storage temp. | 2-8°C | solubility | Soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in cyclohexane. |
Toxicity | LD50 s.c. in mice: 300 mg/kg (Eddy, Sumwalt) |
| CODEINE HYDROCHLORIDE Usage And Synthesis |
Chemical Properties | White or almost white, crystalline powder or small, colourless crystals. | Uses | Opioid receptor agonist; analgesic. | Contact allergens | Codeine has been reported as an occupational sensitizer
in workers in the production of opium alkaloids.
Codeine has been responsible for fixed drug eruptions
or generalized dermatitis. Cross-sensitivity is expected
to morphine. |
| CODEINE HYDROCHLORIDE Preparation Products And Raw materials |
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