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| | Ervamycine Basic information |
| Product Name: | Ervamycine | | Synonyms: | Ervamycine;16-Methoxytabersonine;Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-16-methoxy-, methyl ester, (5α,12R,19α)-;Tabersonine Impurity 3;VincamineImpurity20;Vincamine Impurity 20 (Ervamycine) | | CAS: | 27773-39-3 | | MF: | C22H26N2O3 | | MW: | 366.46 | | EINECS: | | | Product Categories: | | | Mol File: | 27773-39-3.mol |  |
| | Ervamycine Chemical Properties |
| Boiling point | 514.6±50.0 °C(Predicted) | | density | 1.27±0.1 g/cm3(Predicted) | | pka | 7.66±0.60(Predicted) |
| | Ervamycine Usage And Synthesis |
| Description | This alkaloid from Vinca herbacea has been isolated as the crystalline hydrochloride,
m.p. 184-6°C (dec.). The free base has [α]23D - 310° ± 2° (c 0.32,
CHC13). Hydrogenation over Pt02 gives the 6:7-dihydro derivative which has
[α]26D - 412.8° (c 0.606, CHCI3). When heated at 100°C with 5N-HC1, the
latter is simultaneously hydrolyzed and decarboxylated to furnish 16-methoxy-
1: 2-dehydro-( - )-aspidospermidine. | | Definition | ChEBI: 16-methoxytabersonine is the 16-methoxy derivative of tabersonine. It is a monoterpenoid indole alkaloid, an organic heteropentacyclic compound, a methyl ester and a tertiary amino compound. It is functionally related to a tabersonine. It is a conjugate base of a 16-methoxytabersoninium(1+). | | References | Pyuskyulev et al., Collect. Czech. Chem. Commun., 32, 1289 (1967) |
| | Ervamycine Preparation Products And Raw materials |
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