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Suzhou Zhixin Biotechnology Co., Ltd.
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0512-65118909 15162312715 |
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sales@szzxbio.com |
| Products Intro: |
Product Name:HexanolaminoPAFC-16
CAS:137566-83-7
Purity:98%+ Package:1g;10g;100g
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| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
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| Tel: |
021-65675885 18964387627 |
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customer_service@efebio.com |
| Products Intro: |
Product Name:Hexanolamino PAF C-16
CAS:137566-83-7
Purity:98% Package:1mg;5mg;10mg
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| Company Name: |
ApexBio Technology
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+ 1-832-696-8203 |
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sales@apexbt.com |
| Products Intro: |
Product Name:Hexanolamino PAF C-16
CAS:137566-83-7
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| Company Name: |
Cayman Chemical Company
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(800) 364-9897 |
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cayman@caymanchem.com |
| Products Intro: |
Product Name:Hexanolamino PAF C-16
CAS:137566-83-7
Package:>=98% Remarks:60905
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| | PLATELET ACTIVATING FACTOR-16, ANTAGONIST Basic information |
| Product Name: | PLATELET ACTIVATING FACTOR-16, ANTAGONIST | | Synonyms: | PLATELET ACTIVATING FACTOR-16, ANTAGONIST;1-O-HEXADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHO-(N,N,N-TRIMETHYL)-HEXANOLAMINE;1-O-HEXADECYL-2-ACETYL-SN-GLYCEROL-3-PHOSPHO-(N,N,N-TRIMETHYL)HEXANOLAMINE;1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERYL-3-PHOSPHORYL(N,N,N-TRIMETHYL) HEXANOLAMINE;1-O-HEXADECYL-2-O-ACETYL-SN-GLYCERO-3-PHOSPHO-(N,N,N-TRIMETHYL)HEXANOLAMINE;L-ALPHA-PHOSPHATIDYL(N,N,N-TRIMETHYL)HEXANOLAMINE, BETA-ACETYL, GAMMA-HEXADECYL;HEXANOLAMINO PAF C-16;1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphono(N,N,N-trimethyl)hexanolamine | | CAS: | 137566-83-7 | | MF: | C30H62NO7P | | MW: | 579.79 | | EINECS: | | | Product Categories: | | | Mol File: | 137566-83-7.mol |  |
| | PLATELET ACTIVATING FACTOR-16, ANTAGONIST Chemical Properties |
| storage temp. | −20°C | | solubility | ≤23mg/ml in ethanol;0.5mg/ml in DMSO;1.5mg/ml in dimethyl formamide | | form | lyophilized powder |
| | PLATELET ACTIVATING FACTOR-16, ANTAGONIST Usage And Synthesis |
| Uses | 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phospho-(N,N,N-trimethyl)-hexanolamine is a PAF antagonist. | | Definition | ChEBI: 1-o-hexadecyl-2-o-acetyl-sn-glyceryl-3-phosphoryl(n,n,n-trimethyl)hexanolamine is a glycerophospholipid. | | Biological Activity | hexanolamino paf c-16 is a paf analog with paf agonist/antagonist properties.platelet activating factor (paf; c16), a phospholipid mediator of inflammation, is secreted by several cell types including arterial endothelial cells, and can activate polymorphonuclear leucocytes and monocytes via specific cell surface receptors. paf also stimulates the production of active oxygen species by human monocyte - derived macrophages [1].hexanolamino paf c-16, a paf analog with an increased inter-ionic distance in the polar head group, showed a greater potency in macrophages than platelets. in human monocyte-derived macrophages, hexanolamino paf c-16 was an antagonist and specifically inhibited the generation of superoxide ion (02-) and hydrogen peroxide (h202) in response to paf [1]. in both rabbit platelets and guinea-pig macrophages, hexanolamino paf c-16 acted as a partial agonist [2]. | | references | [1]. rouis m, nigon f, chapman mj. platelet activating factor is a potent stimulant of the production of active oxygen species by human monocyte-derived macrophages. biochem biophys res commun. 1988 nov 15;156(3):1293-301.
[2]. stewart ag, grigoriadis g. structure-activity relationships for platelet-activating factor (paf) and analogues reveal differences between paf receptors on platelets and macrophages. j lipid mediat. 1991 nov;4(3):299-308. |
| | PLATELET ACTIVATING FACTOR-16, ANTAGONIST Preparation Products And Raw materials |
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