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| | VU 0364770 Basic information |
| Product Name: | VU 0364770 | | Synonyms: | VU 0364770;2-PyridinecarboxaMide, N-(3-chlorophenyl)-;N-(3-Chlorophenyl)picolinamide;N-(3-chlorophenyl)pyridine-2-carboxamide;VU 0364770 100MG;VU0364770;VU-0364770;VU 0364770 USP/EP/BP;SKL856 | | CAS: | 61350-00-3 | | MF: | C12H9ClN2O | | MW: | 232.67 | | EINECS: | | | Product Categories: | Aromatics, Heterocycles;Inhibitors | | Mol File: | 61350-00-3.mol |  |
| | VU 0364770 Chemical Properties |
| Melting point | 81-83 °C | | Boiling point | 293.6±20.0 °C(Predicted) | | density | 1.341±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 5 mg/ml | | form | Powder | | pka | 11.24±0.70(Predicted) | | color | Light yellow to yellow |
| | VU 0364770 Usage And Synthesis |
| Uses | N-(3-Chlorophenyl)-2-pyridinecarboxamide shows positive allosteric modulation at the mGlu4 receptors in combination with other antagonists resulting in treatment for the neurodegenerative Parkinson’s disease (1). |
| | VU 0364770 Preparation Products And Raw materials |
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