- Way316606 ;Way-316606
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- $0.00 / 1kg
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2024-05-09
- CAS:915759-45-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10000kg
- BenzenesulfonaMide
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- $10.00/ kg
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2024-04-28
- CAS:915759-45-4
- Min. Order: 1kg
- Purity: 99.8%
- Supply Ability: 10000ton
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| | BenzenesulfonaMide, 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoroMethyl)- Basic information |
| Product Name: | BenzenesulfonaMide, 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoroMethyl)- | | Synonyms: | BenzenesulfonaMide, 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoroMethyl)-;WAY 316606;WAY-316606;5-(Phenylsulfonyl)-N-(piperidin-4-yl)-2-(trifluoromethyl)benzenesulfonamide;WAY-316606;WAY 316606;WAY316606;5-(benzenesulfonyl)-N-piperidin-4-yl-2-(trifluoromethyl)benzenesulfonamide;CS-2786;way-316606 /way 316606 | | CAS: | 915759-45-4 | | MF: | C18H19F3N2O4S2 | | MW: | 448.48 | | EINECS: | 1592732-453-0 | | Product Categories: | | | Mol File: | 915759-45-4.mol |  |
| | BenzenesulfonaMide, 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoroMethyl)- Chemical Properties |
| Boiling point | 601.1±65.0 °C(Predicted) | | density | 1.50±0.1 g/cm3(Predicted) | | solubility | DMF: 3 mg/ml; DMSO: 3 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml | | pka | 8.76±0.20(Predicted) | | form | Powder | | color | White to off-white |
| | BenzenesulfonaMide, 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoroMethyl)- Usage And Synthesis |
| Description | WAY-316606 is an inhibitor of secreted frizzled-related protein 1 (sFRP-1; IC50 = 0.5 μM). It increases Wnt signaling in U2OS osteosarcoma cells (EC50 = 0.65 μM). WAY-316606 increases total bone area in a murine calvarial organ culture assay when used at concentrations greater than 0.1 nM. | | Definition | ChEBI: WAY-316606 is a sulfonamide resulting from the formal condensation of the sulfonic acid group of 5-(phenylsulfonyl)-2-(trifluoromethyl)benzenesulfonic acid with the primary amino group of piperidin-4-amine. An inhibitor of secreted Frizzled-Related Protein-1 (sFRP-1). It has a role as a secreted frizzled-related protein 1 inhibitor. It is a sulfone, a sulfonamide, a member of (trifluoromethyl)benzenes, a member of piperidines and a secondary amino compound. |
| | BenzenesulfonaMide, 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoroMethyl)- Preparation Products And Raw materials |
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