GI 254023X manufacturers
- GI254023X
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- $97.00 / 1mg
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2024-11-18
- CAS:260264-93-5
- Min. Order:
- Purity: 98.56%
- Supply Ability: 10g
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| | GI 254023X Basic information |
| Product Name: | GI 254023X | | Synonyms: | GI 254023X;(2R)-N-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]-propyl]-2-[(1S)-1-[formyl(hydroxy)amino]ethyl]-5-phenylpentanamide;GI4023;GI 254023X(GI 4023;SRI 028594);GI 254023X;GI-254023X;GI4023;SRI028594;(2R)-N-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-2-[(1S)-1-(N-hydroxyformamido)ethyl]-5-phenylpentanamide;((2R,3S)-3-(formyl-hydroxyamino)-2-(3-phenyl-1-propyl)butanoic acid [(1S)-2,2-dimethyl-1-methylcarbamoyl-1-propyl] amide) | | CAS: | 260264-93-5 | | MF: | C21H33N3O4 | | MW: | 391.51 | | EINECS: | | | Product Categories: | GI 254023X | | Mol File: | 260264-93-5.mol |  |
| | GI 254023X Chemical Properties |
| density | 1.112±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble15mg/mL, clear | | pka | 8.48±0.69(Predicted) | | form | powder | | color | white to beige |
| | GI 254023X Usage And Synthesis |
| Uses | GI 254023X is an ADAM10 metaloproteinase inhibitor. | | Uses | GI254023X has been used to inhibit ADAM10 (ADAM metallopeptidase domain 10). | | Definition | ChEBI: GI254023X is a L-valine derivative that is 3-methyl-L-valine in which carboxy OH group is replaced by a methylnitrilo group and the one of the amino hydrogens is replaced by a (2R)-2-{(1S)-1-[formyl(hydroxy)amino]ethyl}-5-phenylpentanoyl group. It is a potent MMP9 and ADAM10 metalloprotease inhibitor with IC50 of 2.5 and 5.3 nM, respectively. It has a role as an apoptosis inducer, an antineoplastic agent, a matrix metalloproteinase inhibitor and an EC 3.4.24.* (metalloendopeptidase) inhibitor. It is a L-valine derivative, an aldehyde and a member of hydroxylamines. | | Biochem/physiol Actions | GI254023X is a potent and selective ADAM10 metalloproteinase inhibitor. | | storage | Store at -20°C |
| | GI 254023X Preparation Products And Raw materials |
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