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CGP 71683 HYDROCHLORIDE

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CGP 71683 HYDROCHLORIDE Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: CAS:192322-50-2
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:CGP71683 hydrochloride
CAS:192322-50-2
Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:CGP-71683A HCl
CAS:192322-50-2
Purity:98% Package:5mg Remarks:V18070
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:CGP71683 hydrochloride；CGP71683A
CAS:192322-50-2
Package:1 mg；1 mL * 10mM (in DMSO)；10 mg；100 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:CGP 71683 HYDROCHLORIDE
CAS:192322-50-2
Purity:98%+ Package:500mg;1g;500g；1kg Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
CGP 71683 HYDROCHLORIDE Basic information
Product Name:CGP 71683 HYDROCHLORIDE
Synonyms:CGP 71683 HYDROCHLORIDE;N-[[TRANS-4-[[(4-AMINO-2-QUINAZOLINYL)AMINO]METHYL]CYCLOHEXYL]METHYL]-1-NAPHTHALENESULFONAMIDE HYDROCHLORIDE;CGP 71683;CGP71683HCl;1-Naphthalenesulfonamide, N-[[trans-4-[[(4-amino-2-quinazolinyl)amino]methyl]cyclohexyl]methyl]-, hydrochloride (1:1);UNII-45B73P82A3;CGP-71683A; CGP 71683A; CGP71683A; UNII-45B73P82A3;CGP 71683A hydrochloride
CAS:192322-50-2
MF:C26H30ClN5O2S
MW:512.07
EINECS:
Product Categories:Neuropeptide Y (NPY ) receptor
Mol File:192322-50-2.mol
CGP 71683 HYDROCHLORIDE Structure
CGP 71683 HYDROCHLORIDE Chemical Properties
storage temp. Inert atmosphere,2-8°C
solubility H2O: ~14 mg/mL, soluble
form solid
color off-white
Safety Information
Safety Statements 24/25
WGK Germany 3
MSDS Information
CGP 71683 HYDROCHLORIDE Usage And Synthesis
DescriptionCGP 71683 is an antagonist of neuropeptide Y (NPY) receptor Y5 (IC50 = 1.4 nM in a radioligand binding assay). It is selective for Y5 over Y1, Y2, and Y4 receptors (IC50s = 2,765, 7,187, and 5,637 nM, respectively). It inhibits NPY-induced increases in BT-549 cell growth and MDA-MB-231 cell migration when used at a concentration of 0.25 μM. CGP 71683 (10 mg/kg, i.p.) inhibits increases in food intake induced by intracerebroventricular administration of NPY in rats.
Biological ActivityExtremely selective, non-peptide NPY Y 5 receptor antagonist. Displays > 1000-fold selectivity over Y 1 , Y 2 and Y 4 receptors; IC 50 values are 1.4, 2765, 7187 and 5637 nM at cloned rat Y 5 , Y 1 , Y 2 and Y 4 receptors respectively. Potently inhibits NPY-induced food intake following i.p. administration in diabetic, free-feeding and fasted rats.
storageStore at +4°C
CGP 71683 HYDROCHLORIDE Preparation Products And Raw materials
Tag:CGP 71683 HYDROCHLORIDE(192322-50-2) Related Product Information
CGP 71683 HYDROCHLORIDE W-5 HYDROCHLORIDE