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(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID

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(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:(S)-SNAP5114
CAS:157604-55-2
Purity:98.00% Package:10 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Products Intro: Product Name:SNAP 5114
CAS:157604-55-2
Purity:99% Package:10kg 25kg 200 kilograms per barrel Remarks:good
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525
Email: masar@topule.com
Products Intro: Product Name:(S)-SNAP 5114
CAS:157604-55-2
Purity:98%+ Package:100mg;1g;500g Remarks:Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:(S)-SNAP 5114
CAS:157604-55-2
Purity:>=98%(HPLC) Package:$115.9/5mg;$187.9/10mg;$432.9/25mg;$638.9/50mg;$908.9/100mg;Bulk package Remarks:98%(HPLC)
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Email: 3bsc@sina.com
Products Intro: Product Name:(S)-SNAP 5114;1-[2-[tris(4-Methoxyphenyl)Methoxy]ethyl]-(S)-3-piperidinecarboxylicacid
CAS:157604-55-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID Basic information
Product Name:(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID
Synonyms:(S)-SNAP 5114;(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID;1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-(S)-3-PIPERIDINECARBOXYLIC ACID;S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIP;SNAP 5114 (S)-;(S)-SNAP-5114 >=98% (HPLC), solid;3-Piperidinecarboxylic acid, 1-[2-[tris(4-methoxyphenyl)methoxy]ethyl]-, (3S)-;(S)-SP5114
CAS:157604-55-2
MF:C30H35NO6
MW:505.6
EINECS:
Product Categories:GABA/Glycine receptor
Mol File:157604-55-2.mol
(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID Structure
(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID Chemical Properties
Boiling point 643.9±55.0 °C(Predicted)
density 1.175±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility H2O: insoluble
form solid
pka3.85±0.20(Predicted)
color white
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
MSDS Information
(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID Usage And Synthesis
Uses(S)-SNAP 5114 is a GABA, GAT3 inhibitor.
Biological ActivityGABA transport inhibitor, showing selectivity for GAT-3 and GAT-2 (IC 50 values are 5, 21 and 388 μ M for hGAT-3, rGAT-2 and hGAT-1 respectively). Increases thalamic GABA levels and is an anticonvulsant following systemic administration in vivo .
storageStore at -20°C
references[1]. borden la, dhar tg, smith ke, et al. cloning of the human homologue of the gaba transporter gat-3 and identification of a novel inhibitor with selectivity for this site. receptors channels, 1994, 2(3): 207-213.
[2]. pabel j, faust m, prehn c, et al. development of an (s)-1-{2-[tris(4-methoxyphenyl)methoxy]ethyl}piperidine-3-carboxylic acid [(s)-snap-5114] carba analogue inhibitor for murine γ-aminobutyric acid transporter type 4. chemmedchem, 2012, 7(7): 1245-1255.
[3]. dalby no. gaba-level increasing and anticonvulsant effects of three different gaba uptake inhibitors. neuropharmacology, 2000, 39(12): 2399-2407.
[4]. kataoka k, hara k, haranishi y, et al. the antinociceptive effect of snap5114, a gamma-aminobutyric acid transporter-3 inhibitor, in rat experimental pain models. anesth analg, 2013, 116(5): 1162-1169.
(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID Preparation Products And Raw materials
Tag:(S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID(157604-55-2) Related Product Information
DEMETON S medrylamine CHEMBRDG-BB 4010738 1-(2-benzhydryloxyethyl)piperidine moxastine (S)-1-[2-[TRIS(4-METHOXYPHENYL)METHOXY]ETHYL]-3-PIPERIDINECARBOXYLIC ACID 4,4',4''-TRIMETHOXYTRITYL ALCOHOL Balofloxacin