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| | BETAMETHASONE BUTYRATE PROPIONATE Basic information |
| Product Name: | BETAMETHASONE BUTYRATE PROPIONATE | | Synonyms: | 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-butyrate 21-propionate;Anflavate;Antebate;Betamethasone 17-butyrate 21-propionate;Salex;[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate;[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate;butyric acid [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-3-keto-10,13,16-trimethyl-17-(2-propionyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] ester | | CAS: | 5534-02-1 | | MF: | C29H39FO7 | | MW: | 518.61 | | EINECS: | | | Product Categories: | | | Mol File: | 5534-02-1.mol |  |
| | BETAMETHASONE BUTYRATE PROPIONATE Chemical Properties |
| Melting point | approximate 152℃ | | Boiling point | 613.0±55.0 °C(Predicted) | | density | 1.23±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer, Under inert atmosphere | | solubility | Chloroform (Slightly), Dioxane (Slightly, Sonicated), Methanol (Slightly) | | form | Solid | | pka | 12.88±0.70(Predicted) | | color | White to Off-White |
| | BETAMETHASONE BUTYRATE PROPIONATE Usage And Synthesis |
| Description | Betamethasone butyrate propionate (BBP) was introduced in Japan as a
topical antiinflammatory agent. It is a synthetic corticosteroid with strong
antiinflammatory activity at the site of inflammation but without topical or systemic
side effects. On paper disk granuloma in rats, BBP was shown to have higher
degree of dissociation between antiinflammation efficacy and systemic side effects
than other agents in this class. Antipyretic/analgesic properties have also been
reported. | | Originator | Mitsubishi Kasai (Japan) | | Uses | Betamethasone-17-butyrate-21-propionate are used in the treatment of vitiligo vulgaris with the combination therapy of topical steroid and vitamin D3 compound. | | Definition | ChEBI: Betamethasone butyrate propionate is a corticosteroid hormone. | | Brand name | Antebate; Antevate |
| | BETAMETHASONE BUTYRATE PROPIONATE Preparation Products And Raw materials |
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