- AcS-PEG6-OH
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- $0.00 / 1g
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2024-03-24
- CAS:1352221-63-6
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | S-acetyl-PEG6-alcohol Basic information |
| Product Name: | S-acetyl-PEG6-alcohol | | Synonyms: | S-acetyl-PEG6-alcohol;S-acetyl-PEG6-OH;AcS-PEG6-OH;Ethanethioic acid, S-(17-hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl) ester;S-acetyl-PEG6;S-(17-hydroxy-3,6,9,12,15-pentaoxaheptadecyl) ethanethioate | | CAS: | 1352221-63-6 | | MF: | C14H28O7S | | MW: | 340.43 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1352221-63-6.mol |  |
| | S-acetyl-PEG6-alcohol Chemical Properties |
| Boiling point | 441.7±45.0 °C(Predicted) | | density | 1.134±0.06 g/cm3(Predicted) | | pka | 14.36±0.10(Predicted) |
| | S-acetyl-PEG6-alcohol Usage And Synthesis |
| Biological Activity | S-acetyl-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | S-acetyl-PEG6-alcohol Preparation Products And Raw materials |
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