- Sacubitrilat
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- $41.00 / 1mg
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2024-11-19
- CAS:149709-44-4
- Min. Order:
- Purity: 99.17%
- Supply Ability: 10g
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| | Sacubitril Impurity 7 Basic information |
| Product Name: | Sacubitril Impurity 7 | | Synonyms: | LBQ657;Sacubitrilat;(2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid;LCZ696-4;Diacid of Sacubitril;LCZ-696 Impurity 1;Sacubitrilat (LBQ-657);Sacubitril Desethyl Impurity | | CAS: | 149709-44-4 | | MF: | C22H25NO5 | | MW: | 383.44 | | EINECS: | | | Product Categories: | | | Mol File: | 149709-44-4.mol |  |
| | Sacubitril Impurity 7 Chemical Properties |
| Boiling point | 705.4±60.0 °C(Predicted) | | density | 1?+-.0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMF:30.0(Max Conc. mg/mL);78.24(Max Conc. mM)
DMSO:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.3(Max Conc. mM) | | form | A crystalline solid | | pka | 4.59±0.23(Predicted) | | color | White to off-white |
| | Sacubitril Impurity 7 Usage And Synthesis |
| Uses | Desethyl Sacubitril is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure. |
| | Sacubitril Impurity 7 Preparation Products And Raw materials |
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