| Company Name: |
TOKYO CHEMICAL INDUSTRY CO., LTD.
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| Tel: |
03-36680489 |
| Email: |
Sales-JP@TCIchemicals.com |
| Products Intro: |
Product Name:Biotin-PEG3-acetic Acid
CAS:1189560-96-0
Package:50 mg
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| | Biotin-PEG3-CH2COOH Basic information |
| Product Name: | Biotin-PEG3-CH2COOH | | Synonyms: | Biotin-PEG3-CH2COOH;Biotin-PEG3-acetic Acid;13-oxo-17-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecanoic acid;CAS_1189560-96-0;3,6,9-Trioxa-12-azaheptadecanoic acid, 17-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-13-oxo-;11-(Biotinamido)-3,6,9-trioxaundecanoic Acid;13-oxo-17-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecan-1-oic acid;Biotin-PEG3-CH2COOH/3,6,9-Trioxa-12-azaheptadecanoic acid, 17-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-13-oxo- | | CAS: | 1189560-96-0 | | MF: | C18H31N3O7S | | MW: | 433.52 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1189560-96-0.mol |  |
| | Biotin-PEG3-CH2COOH Chemical Properties |
| | Biotin-PEG3-CH2COOH Usage And Synthesis |
| Biological Activity | Biotin-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Biotin-PEG3-CH2COOH Preparation Products And Raw materials |
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