Related articles - A cinacalcet analog-Evocalcet
- Evocalcet, a novel oral calcimimetic agent, is an allosteric modulator that acts on the calcium-sensing receptors on the membr....
- Dec 26,2023
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| Evocalcet Basic information |
Product Name: | Evocalcet | Synonyms: | Evocalcet;KHK7580;Benzeneacetic acid, 4-[(3S)-3-[[(1R)-1-(1-naphthalenyl)ethyl]amino]-1-pyrrolidinyl]-;2-{4-[(3S)-3-{[(1R)-1-(Naphthalen-1-yl)ethyl]amino}pyrrolidin-1-yl]phenyl}acetic acid;Calcium-sensing receptor,KHK-7580,Inhibitor,KHK 7580,CaSR,Evocalcet,inhibit;Ivocase;MT 4580;MT4580 | CAS: | 870964-67-3 | MF: | C24H26N2O2 | MW: | 374.48 | EINECS: | | Product Categories: | | Mol File: | 870964-67-3.mol | |
| Evocalcet Chemical Properties |
Boiling point | 594.4±50.0 °C(Predicted) | density | 1.23±0.1 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMF:5.0(Max Conc. mg/mL);13.35(Max Conc. mM) DMSO:5.0(Max Conc. mg/mL);13.35(Max Conc. mM) DMSO:PBS (pH 7.2) (1:2):0.3(Max Conc. mg/mL);0.81(Max Conc. mM) | form | A crystalline solid | pka | 4.71±0.10(Predicted) | color | White to off-white |
| Evocalcet Usage And Synthesis |
Uses | 4-[(3S)-3-[[(1R)-1-(1-Naphthalenyl)ethyl]amino]-1-pyrrolidinyl]benzeneacetic Acid is part of a pharmaceutical composition that is a therapeutic agent for hyperparathyroidism. |
| Evocalcet Preparation Products And Raw materials |
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