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Shanghai EFE Biological Technology Co., Ltd.
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021-65675885 18964387627 |
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Product Name:13,14-dihydro-15-keto Prostaglandin E2
CAS:363-23-5
Purity:95% Package:1mg;5mg;10mg
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| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
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400-9205774 |
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sales@glpbio.cn |
| Products Intro: |
Product Name:13,14-dihydro-15-keto Prostaglandin E2
CAS:363-23-5
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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18818260767 |
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sales@chemegen.com |
| Products Intro: |
Product Name:13,14-dihydro-15-keto Prostaglandin E2
CAS:363-23-5
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
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| | 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Basic information |
| Product Name: | 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 | | Synonyms: | 9,15-DIOXO-11ALPHA-HYDROXY-PROST-5Z-EN-1-OIC ACID;15-keto-13,14-dihydroprostaglandine2;13,14-dihydro-15-oxo-prostaglandin E2;13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2;(E)-7-[(1R,2R,3R)-3-hydroxy-5-oxo-2-(3-oxooctyl)cyclopentyl]hept-5-enoic acid;13,14-Dihydro-15-keto-PGE2;13,14-Dihydro-15-ketoprostaglandinE2 solution;(5Z)-11α-Hydroxy-9,15-dioxoprosta-5-ene-1-oic acid | | CAS: | 363-23-5 | | MF: | C20H32O5 | | MW: | 352.47 | | EINECS: | | | Product Categories: | | | Mol File: | 363-23-5.mol |  |
| | 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Chemical Properties |
| Boiling point | 538.1±45.0 °C(Predicted) | | density | 1.086±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | pka | 4.75±0.10(Predicted) |
| | 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Usage And Synthesis |
| Description | 13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is a metabolite of PGE2 and the primary PGE2 metabolite in plasma. It is formed from PGE2 via a 15-keto PGE2 intermediate by 15-oxo-PG Δ13 reductase. Unlike PGE2, 13,14-dihydro-15-keto PGE2 does not bind effectively to the PGE2 receptors EP2 and EP4 expressed in CHO cells (Kis = 12 and 57 μM, respectively) or induce adenylate cyclase activity in the same cells (EC50s = >18 and >38 μM, respectively). Levels of 13,14-dihydro-15-keto PGE2 are increased in the plasma of women in the third trimester of pregnancy and in women during and immediately after labor and delivery. Levels of 13,14-dihydro-15-keto PGE2 levels are decreased in tumor tissue compared to adjacent non-cancerous tissue isolated from patients with non-small cell lung cancer (NSCLC). | | Uses | 13,14-Dihydro-15-ketoPGE2 is a primary metabolite of PGE2 in plasma. | | Definition | ChEBI: The 13,14-dihydro derivative of 15-oxo-prostaglandin E2. |
| | 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Preparation Products And Raw materials |
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