- Clorsulon
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- $0.00 / 1KG
-
2024-11-27
- CAS:60200-06-8
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 100kg
- Clorsulon
-
- $55.00 / 200mg
-
2024-11-19
- CAS:60200-06-8
- Min. Order:
- Purity: 99.44%
- Supply Ability: 10g
- Clorsulon
-
- $55.00 / 200mg
-
2024-11-19
- CAS:60200-06-8
- Min. Order:
- Purity: 99.44%
- Supply Ability: 10g
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| | Clorsulon Basic information |
| | Clorsulon Chemical Properties |
| Melting point | 194-203°C | | Boiling point | 651.7±65.0 °C(Predicted) | | density | 1.800±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 9.16±0.60(Predicted) | | color | White | | CAS DataBase Reference | 60200-06-8(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 2 | | RTECS | CZ9090000 | | HS Code | 29350090 | | Toxicity | LD50 in mice (mg/kg): 761 i.p.; >10,000 orally (Ostlind) |
| | Clorsulon Usage And Synthesis |
| Description | Clorsulon is a sulfonamide antiparasitic agent. It induces swelling and blebbing and reduces motility of F. hepatica mature flukes when used at a concentration of 10 μg/ml. In vivo, clorsulon (3.5-15 mg/kg) reduces the number of flukes in a goat model of F. hepatica infection. It completely eradicates naturally acquired F. hepatica adult flukes in sheep and cattle when administered at a dose of 7 mg/kg. Formulations containing clorsulon have been used in the treatment of liver flukes in sheep and cattle. | | Chemical Properties | Crystalline Solid | | Uses | A benzenedisulfonamide derivative with fasciolicidal activity. Anthelmintic (Trematodes). | | Uses | analgesic, antiinflammatory | | Definition | ChEBI: 4-amino-6-(1,2,2-trichloroethenyl)benzene-1,3-disulfonamide is a sulfonamide and a member of benzenes. | | Brand name | Curatrem [Veterinary] (Merial). | | Veterinary Drugs and Treatments | Clorsulon is approved for use in the treatment of immature and
adult forms of Fasciola hepatica (Liver fluke) in cattle. It is not effective
against immature flukes less than 8 weeks old. It also has activity
against Fasciola gigantica. Although not approved, the drug has
been used in practice in various other species (e.g., sheep, llamas).
It has activity against F. magna in sheep, but is not completely effective
in eradicating the organism after a single dose, thus severely
limiting its clinical usefulness against this parasite. Clorsulon is also
not effective against the rumen fluke (Paramphistomum). |
| | Clorsulon Preparation Products And Raw materials |
| Raw materials | 4-amino-6-(trichlorovinyl)benzene-1,3-disulphonyl dichloride-->Benzenamine, 3-(trichloroethenyl)--->(trichlorovinyl)benzene-->3-Nitro Penta Chloro Ethyl Benzene-->Benzenamine, 3-(1,1,2,2,2-pentachloroethyl)--->Benzenesulfonamide, 2-nitro-4-(1,2,2-trichloroethenyl)--->3-Nitrobenzaldehyde |
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