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Wuhan Chemwish Technology Co., Ltd
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86-027-67849912 |
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sales@chemwish.com |
Products Intro: |
Product Name:Chartreusin CAS:6377-18-0 Purity:98% Package:1g;5g;25g;50g;100g;500g
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| CHARTREUSIN Basic information |
Product Name: | CHARTREUSIN | Synonyms: | CHARTREUSIN;antibioticx-465a;nsc5159;u-7257;chartreusin from streptomyces*chartreusis;LAMBDAMYCIN;10-[[6-Deoxy-2-O-(6-deoxy-3-O-methyl-α-D-galactopyranosyl)-β-D-galactopyranosyl]oxy]-6-hydroxy-1-methylbenzo[h][1]benzopyrano[5,4,3-cde][1]benzopyran-5,12-dione;LaMbdaMycin, NSC 5159, 747, 1293, X465A, G 261A | CAS: | 6377-18-0 | MF: | C32H32O14 | MW: | 640.59 | EINECS: | | Product Categories: | Antibiotic | Mol File: | 6377-18-0.mol | |
| CHARTREUSIN Chemical Properties |
Melting point | 185℃ | alpha | D25 +132.5° (c = 0.2 in pyridine); D25 -33° (c = 0.3 in glacial acetic acid) | Boiling point | 592.39°C (rough estimate) | density | 1.3027 (rough estimate) | refractive index | 1.6130 (estimate) | storage temp. | 2-8°C | solubility | Chloroform (Slightly, Heated), Methanol (Slightly), Pyridine (Slightly) | form | Yellow solid. | pka | 6?+-.0.20(Predicted) | color | Light Yellow to Yellow | Water Solubility | 15mg/L(25 ºC) | Stability: | Hygroscopic |
| CHARTREUSIN Usage And Synthesis |
Uses | Chartreusin is an antiproliferative agent that inhibits topoisomerase II. | Uses | Chartreusin is an antitumor antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA. It inhibits RNA synthesis and causes single-strand scission of DNA via the formation of free radicals. Chartreusin is also a potent inhibitor of topoisomerase II. | Uses | Chartreusin is an antitumour antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA. It inhibits RNA synthesis and causes single-strand scission of DNA via the formation of free radicals. Chartreusin is also a potent inhibitor of topoisomerase II. | Definition | ChEBI: Chartreusin is a glycoside and a benzochromenone. |
| CHARTREUSIN Preparation Products And Raw materials |
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