- CDAP
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- $0.00 / 1kg
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2024-06-18
- CAS:59016-56-7
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 50000kg
- CDAP
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- $6.00 / 1KG
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2024-03-29
- CAS:59016-56-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| Product Name: | CDAP | | Synonyms: | N-CYANO-4-DIMETHYLAMINOPYRIDINIUM TETRA FLUOROBORATE;1-CYANO-4-DIMETHYLAMINO-PYRIDINIUM TETRAFLUOROBORATE;CDAP;CDAP N-Cyano-4-dimethylaminopyridinium tetrafluoroborate;1-Cyano-4-dimethylaminopyridinium tetrafluoroborate,97+%;N-Cyano-4-diMethylaMinopyridiniuM tetrafluoroborat;4-(DiMethylaMino)pyridin-1-iuM-1-carbonitriletetrafluoroborate;4-(dimethylamino)pyridin-1-ium-1-carbonitrile | | CAS: | 59016-56-7 | | MF: | C8H10BF4N3 | | MW: | 234.99 | | EINECS: | | | Product Categories: | proteinmod | | Mol File: | 59016-56-7.mol |  |
| Melting point | 196-200°C | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | form | Powder | | color | White to yellow | | biological source | synthetic | | Water Solubility | Soluble in water, and acetonitrile. | | λmax | 301nm(CH3CN)(lit.) | | BRN | 5685616 |
| Chemical Properties | White to yellow powder | | Uses | 1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate is a cyanylation reagent for protein sulfhydryl groups and used to prepare protein-polysaccharide conjugates. It is employed as an activating agent for polysaccharide resins and conjugation of lipopolysaccharides while retaining endotoxic activity. | | Biological Activity | CDAP is a cyanylation reagent for protein sulfhydryl groups which is used to prepare protein-polysaccharide conjugates. CDAP is also an activating agent for polysaccharide resins and is used for the conjugation of lipopolysaccharides while retaining their endotoxic activity.
CDAP is considered to be a less toxic reagent as compared to cyanogen bromide (CNBr) (a known polysaccharides activator). In addition, CDAP is easier to use as it can be employed at a lower pH and has fewer side reactions. It is known th at CDAP polysaccharide activation efficiency is optimal at pH 9-10. It was also reported th at direct conjugation of protein to CDAP-activated polysaccharides can be performed under mildly alkaline conditions (pH 7-9). It has also been reported th at proteins could also be conjugated to CDAP-activated polysaccharides at pH 5. |
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