|
|
| | 5-PYRIDIN-4-YL-1H-INDAZOLE Basic information |
| | 5-PYRIDIN-4-YL-1H-INDAZOLE Chemical Properties |
| Boiling point | 419.1±20.0 °C(Predicted) | | density | 1.270±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMF (Slightly), DMSO (Slightly) | | form | Solid | | pka | 13.13±0.40(Predicted) | | color | Pale Yellow |
| | 5-PYRIDIN-4-YL-1H-INDAZOLE Usage And Synthesis |
| Uses | TG693 is an orally active inhibitor of CLK1. TG693 regulates the mutated exon 31 of the dystrophin gene in vivo. TG693 is used in Duchenne muscular dystrophy (DMD) research[1]. | | References | [1] Sako Y, et al. Development of an orally available inhibitor of CLK1 for skipping a mutated dystrophin exon in Duchenne muscular dystrophy. Sci Rep. 2017 May 30;7:46126. DOI:10.1038/srep46126 |
| | 5-PYRIDIN-4-YL-1H-INDAZOLE Preparation Products And Raw materials |
|