| Company Name: |
J & K SCIENTIFIC LTD.
|
| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Capecitabine-d11
CAS:1132662-08-8
Package:10Mg,1Mg
|
- Capecitabine-D11
-
- $0.00 / 5mg
-
2023-05-27
- CAS:1132662-08-8
- Min. Order: 1mg
- Purity: 96%
- Supply Ability: 50mg
|
| | CAPECITABINE-D11 Basic information |
| | CAPECITABINE-D11 Chemical Properties |
| Melting point | 45-50°C | | storage temp. | -20°C Freezer, Under Inert Atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | form | Solid | | color | Off-White to Pale Yellow |
| | CAPECITABINE-D11 Usage And Synthesis |
| Description | Capecitabine-d11 is intended for use as an internal standard for the quantification of capecitabine by GC- or LC-MS. Capecitabine is a prodrug form of 5-fluorouracil (5-FU). It is converted to 5-FU via several enzymatic steps beginning in the liver and ending with conversion in tumor tissue by thymidine phosphorylase, an enzyme that is more concentrated in tumor tissue compared with normal tissue. Capecitabine is cytotoxic only at high concentrations in Scaber, SIHA, and MKN45 cells (IC50s = 97, 578, and 994 μM, respectively) and is inactive in a variety of cancer cell lines, including COLO 205, HCT116, and MCF-7 cells (IC50s = >1,000 μM). | | Chemical Properties | Off-White Powder | | Uses | Capecitabine D11 is an isotopically labelled antineoplastic agent. A prodrug of Doxifluridine.;Labeled Capecitabine, intended for use as an internal standard for the quantification of Capecitabine by GC- or LC-mass spectrometry. | | Uses | An isotopically labelled antineoplastic agent. A prodrug of Doxifluridine (D556750). |
| | CAPECITABINE-D11 Preparation Products And Raw materials |
|