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| 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE Basic information |
| 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE Chemical Properties |
Boiling point | 424.5±30.0 °C(Predicted) | density | 1.129±0.06 g/cm3(Predicted) | storage temp. | Sealed in dry,Room Temperature | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml; Ethanol: slightly | form | A crystalline solid | color | Light yellow to yellow |
| 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE Usage And Synthesis |
Description | O4I1 is an inducer of Oct3/4 expression and translation in diverse human cell lines (increases Oct3/4 mRNA in HEK293 cells by 2.5- and 4-fold at 10 and 20 μM, respectively). It also induces Oct3/4 expression and translation in terminally differentiated human fibroblasts. Through this action, O4I1 promotes the expression of pluripotency-associated genes in human neonatal foreskin fibroblasts. | Uses | O4I1 is a potent Oct3/4 inducer. It promotes expression and stabilization of Oct3/4, and also enhanced its transcriptional activity in human somatic cells, making it useful in regenerative medicine. |
| 2-(4-[(4-METHOXYBENZYL)OXY]PHENYL)ACETONITRILE Preparation Products And Raw materials |
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