碘昔兰
| 中文名称 | 碘昔兰 |
|---|---|
| 中文同义词 | 碘昔兰;碘昔兰 USP标准品;化合物 T19377 |
| 英文名称 | IOXILAN (400 MG) |
| 英文同义词 | IOXILAN (400 MG);5-[Acetyl(2,3-dihydroxypropyl)aMino]-N1-(2,3-dihydroxypropyl)-N3-(2-hydroxyethyl)-2,4,6-triiodo-1,3-benzenedicarboxaMide;1,3-Benzenedicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N-(2,3-dihydroxypropyl)-N'-(2-hydroxyethyl)-2,4,6-triiodo-;Ioxitol;Oxilan 300;5-[acetyl(2,3-dihydroxypropyl)amino]-3-N-(2,3-dihydroxypropyl)-1-N-(2-hydroxyethyl)-2,4,6-triiodobenzene-1,3-dicarboxamide;1,3-Benzenedicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N1-(2,3-dihydroxypropyl)-N3-(2-hydroxyethyl)-2,4,6-triiodo-;Ioxilan (1345206) |
| CAS号 | 107793-72-6 |
| 分子式 | C18H24I3N3O8 |
| 分子量 | 791.11 |
| EINECS号 | |
| 相关类别 | Amines;Aromatics;Diagnostic;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol文件 | 107793-72-6.mol |
| 结构式 |  |
碘昔兰 性质
| 沸点 | 827.8±65.0 °C(Predicted) |
|---|---|
| 密度 | 2.205±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 二甲基亚砜：≥250mg/mL（316.01毫摩尔） |
| 酸度系数(pKa) | 11.47±0.46(Predicted) |
| 形态 | 固体 |
| 颜色 | 白色至米白色 |
| EPA化学物质信息 | 1,3-Benzenedicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N1-(2,3-dihydroxypropyl)-N3-(2-hydroxyethyl)-2,4,6-triiodo- (107793-72-6) |
As a low-osmolar nonionic monomer, Ioxilan increases the safety and tolerance of X-ray contrast agents. The development of Ioxilan is based on the introduction of a double methylene as a hydrophobic region and masking it with a hydrophilic hydroxyl group could lower the osmolality without adversely affecting the biological tolerance.
Rapid intravenous injection of water-soluble X-ray contrast agents (Ioxilan) can be performed with dynamic computed tomography to improve the detectability of liver lesions. When injected intravenously, water-soluble, intravenous X-ray contrast agents are largely distributed in the extracellular fluid space and excreted unchanged by the kidneys. Contrast enhancement of a region of interest depends on the route of administration, delivery of the agent to the area by blood flow, and the final iodine concentration in the region.
安全信息
| 海关编码 | 2924296000 |
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