Company Name: |
J & K SCIENTIFIC LTD.
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Tel: |
010-82848833 400-666-7788 |
Email: |
jkinfo@jkchemical.com |
Products Intro: |
Product Name:Flurbiprofen-d3 CAS:1185133-81-6 Package:50Mg,5Mg
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Company Name: |
ChemStrong Scientific Co.,Ltd
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Tel: |
0755-0755-66853366 13670046396 |
Email: |
sales@chem-strong.com |
Products Intro: |
Product Name:Flurbiprofen-d3 CAS:1185133-81-6 Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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Company Name: |
Artis Biotech Co. Ltd.
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Tel: |
0575-18780151478 18582380095 |
Email: |
sales@artisbio.com |
Products Intro: |
Product Name:Flurbiprofen-d3 Purity:98% HPLC Package:1mg 、5mg、10mg、50mg、 100mg、1g
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| FLURBIPROFEN-D3 Basic information |
| FLURBIPROFEN-D3 Chemical Properties |
Melting point | 108-110°C | storage temp. | -20°C Freezer | solubility | DMF: 25 mg/ml,DMSO: 10 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 0.9 mg/ml | form | A solid | color | White to off-white |
| FLURBIPROFEN-D3 Usage And Synthesis |
Description | Flurbiprofen-d3 is intended for use as an internal standard for the quantification of flurbiprofen (Item Nos. 70250 | 10004207 | 70255) by GC- or LC-MS. Flurbiprofen is a non-selective COX inhibitor (IC50s = 0.04 and 0.51 μM for COX-1 and COX-2, respectively). In vivo, flurbiprofen (0.3-4.8 mg/kg, p.o.) reduces carrageenan-induced hind paw edema and yeast-induced fever in rats. Flurbiprofen reduces plasma fibrinogen levels and arthritic score in a rat model of adjuvant-induced arthritis. It also reduces tumor weight and prostaglandin production and increases survival in a WHT-NC mouse xenograft model when administered at a dose of 5 mg/kg. Formulations containing flurbiprofen have been used to manage pain and inflammation associated with arthritis. | Chemical Properties | White Solid | Uses | An isotopically labelled analog of Flurbiprofen (F598700). | Uses | An Isotopically labeled analog of Flurbiprofe |
| FLURBIPROFEN-D3 Preparation Products And Raw materials |
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