- CGP 52432
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- $1.00 / 1g
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2019-12-26
- CAS:139667-74-6
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 200kg
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| CGP 52432 Basic information |
Product Name: | CGP 52432 | Synonyms: | 3-([[[(3,4-DICHLOROPHENYL)METHYL]AMINO]PROPYL] DIETHOXYMETHYL)PHOSPHINIC ACID;CGP 52432;CGP 52432;CGP-52432;CGP 52432;P52432;Phosphinic acid, P-[3-[[(3,4-dichlorophenyl)methyl]amino]propyl]-P-(diethoxymethyl)-;CGP52432 >=98% (HPLC);(3-((3,4-dichlorobenzyl)amino)propyl)(diethoxymethyl)phosphinic acid;Inhibitor,CGP-52432,inhibit,Gamma-aminobutyric acid Receptor,CGP52432,GABA Receptor,γ-Aminobutyric acid Receptor | CAS: | 139667-74-6 | MF: | C15H24Cl2NO4P | MW: | 384.24 | EINECS: | 000-000-0 | Product Categories: | GABA/Glycine receptor;GABA | Mol File: | 139667-74-6.mol | |
| CGP 52432 Chemical Properties |
Boiling point | 544.4±50.0 °C(Predicted) | density | 1.258±0.06 g/cm3(Predicted) | storage temp. | 2-8°C | solubility | H2O: soluble1mg/mL, clear (warmed) | pka | 2.26±0.50(Predicted) | form | powder | color | white to beige | Water Solubility | Soluble in water (10mM, gentle warming) |
| CGP 52432 Usage And Synthesis |
Uses | CGP52432 has been used as a γ-aminobutyric acid B (GABAB) antagonist:
- to study its effects on the simulation of the onset of status epilepticus (SE) in mice
- for voltage-clamp recording in mice neurons
- to study its effects on the GABAB receptor-mediated neurotransmission in guinea pig hippocampus
| Definition | ChEBI: 3-[(3,4-dichlorophenyl)methylamino]propyl-(diethoxymethyl)phosphinic acid is a dichlorobenzene. | Biological Activity | Potent, selective GABA B receptor antagonist (IC 50 = 85 nM). | Biochem/physiol Actions | CGP52432 participates in inhibiting the glycine overflow in the hippocampus. | storage | +4°C (desiccate) |
| CGP 52432 Preparation Products And Raw materials |
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