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| | Fmoc-O-(benzylphospho)-L-serine Basic information |
| | Fmoc-O-(benzylphospho)-L-serine Chemical Properties |
| density | 1.403±0.06 g/cm3(Predicted) | | storage temp. | Store at -15°C to -25°C. | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 1.42±0.50(Predicted) | | color | White to off-white | | Water Solubility | Slightly soluble in water. | | BRN | 7060483 | | CAS DataBase Reference | 158171-14-3(CAS DataBase Reference) |
| WGK Germany | 3 | | F | 10-21 | | HS Code | 2924 29 70 |
| | Fmoc-O-(benzylphospho)-L-serine Usage And Synthesis |
| Chemical Properties | White to off-white powder | | Uses | It can be applied in the synthesis of phosphopeptides. This derivative can be introduced using standard activation methods, such as PyBOP and TBTU. The monoprotected phosphoserine residue once incorporated is stable to piperidine. Using this reagent, even peptides containing multiple phosphorylation sites can be prepared efficiently by standard Fmoc SPPS methods. β-piperidinylalanine formation has been shown to occur during Fmoc deprotection of N-terminal Ser(PO(OBzl)OH), particularly under microwave conditions. This side reaction can be eliminated by using cyclohexylamine or DBU just for this Fmoc deprotection step . | | Uses | Building block for the synthesis of phosphoserine containing peptides. |
| | Fmoc-O-(benzylphospho)-L-serine Preparation Products And Raw materials |
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