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Pyridoxine hydrochloride

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CAS:58-56-0
Purity:99 Package:5KG;1KG Remarks:api
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CAS:58-56-0
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CAS:58-56-0
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CAS:58-56-0
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Pyridoxine hydrochloride manufacturers

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  • $0.00 / 1Kg/Bag
  • 2024-12-25
  • CAS:58-56-0
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  • Purity: 99% up, High Density
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Related articles

  • What is Pyridoxine hydrochloride?
  • Pyridoxine hydrochloride is the hydrochloride salt of Vitamin B6. Vitamin B6 (B6) is a water-soluble vitamin, which can be fou....
  • Feb 17,2020
Pyridoxine hydrochloride Basic information
Nutrition supplements
Product Name:Pyridoxine hydrochloride
Synonyms:hexabionehydrochloride;hexavibex;hexermin;hexobion;paxadon;Pridoxinehydrochloride;pyridipca;pyridox
CAS:58-56-0
MF:C8H12ClNO3
MW:205.64
EINECS:200-386-2
Product Categories:Inhibitors;Vitamin Ingredients;vitamin;Nutritional Supplements;Vitamins and derivatives;Aromatics;Heterocycles;Biochemistry;Pyridinium Compounds;Vitamins;Vitamin series;Isolabel;58-56-0
Mol File:58-56-0.mol
Pyridoxine hydrochloride Structure
Pyridoxine hydrochloride Chemical Properties
Melting point 214-215 °C(lit.)
density 1.2784 (rough estimate)
vapor density 7.1 (vs air)
refractive index 1.5800 (estimate)
Fp 9℃
storage temp. room temp
solubility H2O: 0.1 g/mL at 20 °C, clear, colorless
form Crystalline Powder
color White to almost white
PH Range3.2
Water Solubility 0.1 g/mL (20 ºC)
Sensitive Light Sensitive
Merck 14,7982
BRN 3632435
BCS Class1
Stability:Stable. Protect from air and light.
LogP-1.098 (est)
CAS DataBase Reference58-56-0(CAS DataBase Reference)
EPA Substance Registry System5-Hydroxy-6-methyl-3,4-pyridinedimethanol, hydrochloride (58-56-0)
Safety Information
Hazard Codes Xi,T,F
Risk Statements 36/37/38-39/23/24/25-23/24/25-11
Safety Statements 26-37/39-45-36/37-16-7-24/25
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 2
RTECS UV1350000
8-10
TSCA Yes
HS Code 29362500
Hazardous Substances Data58-56-0(Hazardous Substances Data)
MSDS Information
Pyridoxine hydrochloride Usage And Synthesis
Nutrition supplements
Pyridoxine hydrochloride(58-56-0) is the hydrochloride salt of Vitamin B6. Vitamin B6 (B6) is a water-soluble vitamin, which can be found in various foods such as fish, poultry, whole grains, legumes, banana, nuts, and sesame.Vitamin B6 has an important role in the metabolism of amino acids as a coenzyme, pyridoxal 5'-phosphate. 
B6 may exert an anticolon tumor effect by the protection of the colon epithelium from damage in rats treated with 1,2-dimethylhidrazine (DMH) and to decreased lithocholic acid, a colon carcinogen. Vitamin B6 may prevent such diseases by lowering inflammation. 
Chemical PropertiesWhite or almost white, crystalline powder.
UsesPyridoxine Hydrochloride is an acid form of vitamin b6, a water- soluble vitamin. it is soluble in water, and slightly soluble in alco- hol. it is slowly affected by sunlight and is reasonably stable in air. it has a ph of 2.3–3.5. it is also termed vitamin b6 hydrochloride. see pyridoxine.
DefinitionChEBI: Pyridoxine hydrochloride is the hydrochloride salt of pyridoxine. It is a hydrochloride and a vitamin B6. It contains a pyridoxine.
ApplicationPyridoxine hydrochloride has been used:
As a vitamin component in a chemically defined diet with balanced metal content for metal depletion studies;
As a component of chemically defined medium (CDM) to culture Staphylococcus aureus WSPPA;
As analytical reference standards for the determination of analytes in pharmaceutical preparations by chromatography and spectrophotometric techniques;
As a vitamin to study the impact of protein expression and post-translational modifications specifically charge heterogeneity;
As a medicine, it is used to prevent or treat certain neurological disorders (peripheral neuropathy) caused by certain drugs (e.g. isoniazid). It is also used in the treatment of certain hereditary disorders (e.g. flavoururic aciduria, hyperoxaluria, homocystinuria).
Brand nameHexa-Betalin (Lilly).
General DescriptionVitamin B6 has six forms namely, pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. Pyridoxine hydrochloride primarily treats vitamin B6 deficiency and helps alleviate nausea and vomiting during pregnancy. It exists in various forms, including pyridoxine, pyridoxal, and pyridoxamine, which convert into the active coenzyme pyridoxal 5-phosphate (PLP or P5P) in the body.
Biochem/physiol ActionsVitamin B6 is an essential coenzyme for amino acid, carbohydrate and lipid metabolism. Pyridoxine serves as a primary source in multivitamins. Pyridoxine deficiency is associated with peripheral neuropathy.
Clinical UseVitamin B6
Side effectsCommon side effects of Pyridoxine hydrochloride include: headache, nausea, drowsiness, mild numbness or tingling. Serious allergic reactions are rare and include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing, decreased sensation of touch, temperature, and vibration; loss of balance or coordination. If serious side effects occur please seek medical attention.
Safety ProfilePoison by intravenous route. Moderately toxic by ingestion, intramuscular, and subcutaneous routes. Human reproductive effects by ingestion and intramuscular routes: postpartum changes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl.
MetabolismPyridoxine hydrochloride is metabolised to its active form pyridoxamine phosphate. It is stored mainly in the liver where there is oxidation to 4-pyridoxic acid and other inactive metabolites which are excreted in the urine.
Purification MethodsPurify the vitamin by recrystallisation from EtOH/Me2CO, n-BuOH or MeOH/Et2O. Its solubility in H2O is 22%, and in EtOH it is 1.1%. It is insoluble in Et2O and CHCl3. Acidic aqueous solutions are stable at 120o/30minute. The free base has m 159-160o after recrystallisation from Me2CO and sublimation at 140-145o/0.0001mm. It has UV max at 290nm ( 84,000), 253 and 325nm ( 3,700 and 7,100) in 0.1N aqueous HCl. [Khua & Wendt Chem Ber 71 780 1938, 72 311 1939, Harris & Folkers J Am Chem Soc 61 1242 1939, Harris et al. J Am Chem Soc 62 3198 1940, Beilstein 21/5 V 492.]
Tag:Pyridoxine hydrochloride(58-56-0) Related Product Information
Methoxyammonium chloride Bensulfuron methyl Methylparaben L-Lysine hydrochloride 1-AdaMantanethylaMine Topotecan hydrochloride Pyridine hydrochloride Kresoxim-methyl Thiophanate-methyl Diphenhydramine Hydrochloride Pyridoxamine dihydrochloride CHLOROPHOSPHONAZO III 2-Hydroxy-4-methylpyridine Triethylamine hydrochloride 2,2-Bis(hydroxymethyl)propionic acid D-Glucosamine hydrochloride 4-Pyridineacetic acid hydrochloride VITAMIN B6 HYDROCHLORIDE,VITAMIN B6, HCL,B6-PYRIDOXINE HYDROCHLORIDE