- Brodimoprim USP/EP/BP
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- $1.10 / 1g
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2021-07-17
- CAS:56518-41-3
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
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| Brodimoprim Basic information |
| Brodimoprim Chemical Properties |
Melting point | 225-228° | storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere | solubility | DMSO (Slightly), Methanol (Sparingly) | pka | 7.15(at 25℃) | form | Solid | color | White to Pale Yellow | Stability: | Light Sensitive |
| Brodimoprim Usage And Synthesis |
Description | Brodimoprim, a dihydrofolate reductase inhibitor, was introduced for the treatment of
common infections of upper respiratory tract such as sinusitis and exacerbation of chronic
bronchitis. It has a broad spectrum of antimicrobial activities against most Gram-positive and
-negative pathogens including some bacterial strains that are resistant to amoxicillin, a widely
used antibiotic for the indicated infections. Brodimoprim also has a favorable pharmacokinetic
profile exemplified by its long half-life and good tissue penetration. | Chemical Properties | Off-White to Pale Yellow Solid | Originator | Helsinn (Switzerland) | Uses | A structural derivative of Trimethoprim (T795615). A selective dihydrofolate reductase inhibitor; diaminopyridine antibacterial agent. | Definition | ChEBI: An aminopyrimidine that is 2,4-diaminopyrimidine in which the hydrogen at position 5 has been replaced by a 4-bromo-3,5-dimethoxybenzyl group. | Brand name | Hyprim;Unitrim |
| Brodimoprim Preparation Products And Raw materials |
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