- Phosphinothricin
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- $10.00 / 1kg
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2023-08-09
- CAS:51276-47-2
- Min. Order: 1kg
- Purity: 99.99%
- Supply Ability: 50000tons
- Glufosinate
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- $0.00 / 1Kg/Bag
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2020-11-16
- CAS:51276-47-2
- Min. Order: 10Kg/Bag
- Purity: 99%
- Supply Ability: 20 Tons
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| | Phosphinothricin Basic information |
| Product Name: | Phosphinothricin | | Synonyms: | 2-amino-4-(hydroxymethylphosphinyl)butyric acid;Phosphinothricin;Phosphinothricin ammonium salt;2-Amino-4-(methylhydroxyphosphinyl)butyric acid;HOE-35956;HOE-866;C05042;IAJOBQBIJHVGMQ-UHFFFAOYSA-N | | CAS: | 51276-47-2 | | MF: | C5H12NO4P | | MW: | 181.13 | | EINECS: | 257-102-5 | | Product Categories: | | | Mol File: | 51276-47-2.mol |  |
| | Phosphinothricin Chemical Properties |
| Melting point | 229-231° (dec) | | Boiling point | 519.1±45.0 °C(Predicted) | | density | 1.378±0.06 g/cm3(Predicted) | | solubility | Aqueous Acid (Slightly), Methanol (Very Slightly, Sonicated), Water (Slightly) | | pka | 2.22±0.10(Predicted) | | form | Solid | | color | White to Light Beige | | Stability: | Hygroscopic | | LogP | -0.750 (est) | | EPA Substance Registry System | Butanoic acid, 2-amino-4-(hydroxymethylphosphinyl)- (51276-47-2) |
| | Phosphinothricin Usage And Synthesis |
| Definition | ChEBI: 2-amino-4-[hydroxy(methyl)phosphoryl]butanoic acid is a non-proteinogenic alpha-amino acid that is 2-aminobutanoic acid which is substituted at position 4 by a hydroxy(methyl)phosphoryl group. It is a member of phosphinic acids and a non-proteinogenic alpha-amino acid. | | Enzyme inhibitor | This dephospho transition-state analogue (FW = 177.10 g/mol; CAS 51276- 47-2) is naturally occurring glutamate analogue, first isolated from Streptomyces viridochromogenes. Phosphonothricin is a slow, tight-binding inhibitor of glutamine synthetase that binds at the glutamate binding site and stabilizes the flap of a glutamyl residue in a position blocking glutamate entry into the active site, thereby trapping the inhibitor on the enzyme. Phosphinothricin undergoes an ATP-dependent phosphorylation. Note: Phosphinothricin is a component of the antibiotics bialaphos and phosalacine. The monoammonium salt of the racemic compound, also called glufosinate-ammonium, is a post-emergent herbicide. | | Metabolic pathway | When 14C-phosphinothricin [homoalanin-4-yl-
(methyl)phosphinic acid] is incubated in the cell
suspension cultures of soybean, wheat, and maize, in
maize cells which take up to 50% of the applied
radioactivity, four different metabolites are detected
which are identified as 4-methylphosphinico-2-oxo-
butyric acid, 4-methylphosphinico-2-hydroxybutyric
acid, 4-methylphosphinicobutyric acid, and 3-
methylphosphinicopropionic acid. In soybean and
wheat cultures, 10 and 6% of the applied radioactivity
is taken up, respectively. In soybean, only one
metabolite, 3-methylphosphinicopropionic acid, is
detected, whereas in wheat, 4-methyl-
phosphinicobutyric acid is additionally present. |
| | Phosphinothricin Preparation Products And Raw materials |
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