Company Name: |
J & K SCIENTIFIC LTD.
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Tel: |
010-82848833 400-666-7788 |
Email: |
jkinfo@jkchemical.com |
Products Intro: |
Product Name:9-epi-Quinidine CAS:572-59-8 Package:100Mg,1g
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Company Name: |
Chemsky (shanghai) International Co.,Ltd
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Tel: |
021-50135380 |
Email: |
shchemsky@sina.com |
Products Intro: |
Product Name:9-epi-Quinidine;(9R)- CAS:572-59-8 Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
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Company Name: |
Guangzhou Isun Pharmaceutical Co., Ltd
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Tel: |
020-39119399 18927568969 |
Email: |
isunpharm@qq.com |
Products Intro: |
Product Name:Epiquinidine CAS:572-59-8 Purity:97.0% Package:1g; 5g; 10g; 50g; 100g;
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| (9R)-6'-methoxycinchonan-9-ol Basic information |
| (9R)-6'-methoxycinchonan-9-ol Chemical Properties |
Melting point | 111-113° | alpha | D25 +107.8° (c = 1.02 in ethanol) | Boiling point | 462.75°C (rough estimate) | density | 1.1294 (rough estimate) | refractive index | 1.5700 (estimate) | storage temp. | 2-8°C | form | Solid-Liquid Mixture | pka | 12.80±0.20(Predicted) | color | White to off-white |
| (9R)-6'-methoxycinchonan-9-ol Usage And Synthesis |
Description | This alkaloid is stereoisomeric with epiQuinine and occurs in 'Quinoidine', the
mixture of amorphous bases left after extraction of the four primary alkaloids of
Cinchona bark. It crystallizes in colourless leaflets from Et20 and is fluorescent
in dilute H2S04, It is dextrorotatory with [α]19D + 102.4° (c 0.8648, EtOH) and
furnishes a dihydrochloride, m.p. 195-6°C (dec.); [α]20D + 45.5° (c 0.8012,
EtOH); a hydrobromide, m.p. 240°C; thiocyanate, m.p. 193°C; [α]20D + 44.5°
(H20) and the dibenzoyl-(+)-tartrate, m.p. 167°C; [α]201D + 3.7° (c 0.8068,
EtOH-CHCI 3 ). Catalytic hydrogenation with Pd gives the dihydro derivative,
m.p. 122°C; [α]22D + 73.1° (c 0.766, EtOH). | Uses | The 9-epimer of Quinidine (Q685000). Antimalarial. | References | Thron, Dirscherl., Annalen, 521,48 (1935) |
| (9R)-6'-methoxycinchonan-9-ol Preparation Products And Raw materials |
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