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SynAsst Chemical.
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021-60343070 |
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Products Intro: |
Product Name:2-AMino-N-(4-(diethylaMino)-2-Methylphenyl)benzaMide CAS:16231-75-7 Purity:96%Min Package:10g 100g 500g
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| Atolide Basic information |
Product Name: | Atolide | Synonyms: | 2-Amino-N-(4-diethylamino-2-methylphenyl)benzamide;Go 1213;W 5733;Atolide;Benzamide, 2-amino-N-[4-(diethylamino)-2-methylphenyl]- | CAS: | 16231-75-7 | MF: | C18H23N3O | MW: | 297.39 | EINECS: | | Product Categories: | | Mol File: | 16231-75-7.mol | |
| Atolide Chemical Properties |
Melting point | 153-154 °C | Boiling point | 415.7±45.0 °C(Predicted) | density | 1.153±0.06 g/cm3(Predicted) | pka | 12.87±0.70(Predicted) |
| Atolide Usage And Synthesis |
Originator | Atolide,ZYF Pharm Chemical | Uses | Anticonvulsant. | Manufacturing Process | 0.8 kg (4.5 moles) of freshly distilled 2-amino-5-diethylaminotoluene is mixed
thoroughly with 0.75 kg (4.5 moles) of isatoic acid anhydride and the mixture
heated to 100°C with stirring for three hours. The product formed is taken up
before cooling in 2.5 liters of boiling ethyl acetate and the solution filtered. On
cooling the filtrate 1.1 kg (83% of theory) of 2-amino-4'-(diethylamino)-2'-
methylbenzanilide precipitates out. After re-crystallzation from n-propanol the
colorless crystalline product obtained melts at 152°C. | Therapeutic Function | Anticonvulsant |
| Atolide Preparation Products And Raw materials |
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