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ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE

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ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:BMY-14802 hydrochloride；BMY 14802 hydrochloride
CAS:105565-55-7
Package:10 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel: +86-057181025280; +8617767106207
Email: sales@molcore.com
Products Intro: Product Name:BMY-14802-1
CAS:105565-55-7
Purity:98% Min. Remarks:MC34198
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:BMY 14802 hydrochloride
CAS:105565-55-7
Purity:>=98%(HPLC) Package:$86.9/5mg;$137.9/10mg;$291.9/25mg;$494.9/50mg;Bulk package Remarks:98%(HPLC)
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Email: 3bsc@sina.com
Products Intro: Product Name:BMY 14802 hydrochloride;α-(4-Fluorophenyl)-4-(5-fluoro-2-pyriMidinyl)-1-piperazinebutanolhydrochloride
CAS:105565-55-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Company Name: EMMX Biotechnology LLC  
Tel: 888-539-0666
Email: info@emmx.com
Products Intro: Product Name:BMY 14802 hydrochloride
CAS:105565-55-7
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE Basic information
Product Name:ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE
Synonyms:ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE;BMY 14802 HYDROCHLORIDE;BMY14802HyClHCl;BMS-181100;BMY-14802-1;α-(4-Fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazinebutanolhydrochloride
CAS:105565-55-7
MF:C18H23ClF2N4O
MW:384.85
EINECS:
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Mol File:105565-55-7.mol
ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE Structure
ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE Chemical Properties
storage temp. Desiccate at RT
solubility <9.62mg/ml in H2O
form solid
color White
Water Solubility Soluble to 25 mM in water
Safety Information
MSDS Information
ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE Usage And Synthesis
UsesBMY 14802 Hydrochloride was studied to be a potential atypical antipsychotic agent.
Biological ActivityPotent sigma receptor antagonist (IC 50 = 112 nM) with modest to weak affinity for 5-HT 1A and α 1 receptors. Antipsychotic following oral administration and acts via indirect modulation of central dopaminergic systems.
in vitrobmy 14802 has its most potent binding at the sigma binding site, with some degree of serotonin subtype 1a and negligible dopamine receptor binding [1].
in vivobmy 14802 is atypical of standard neuroleptics in that it does not induce catalepsy in rats. in addition, it has been shown to have efficacy in animal models of psychosis [1].
IC 50112 nm for (+)-[3h]-3-ppp
references[1] gewirtz gr, gorman jm, volavka j, macaluso j, gribkoff g, taylor dp, borison r. bmy 14802, a sigma receptor ligand for the treatment of schizophrenia. neuropsychopharmacology. 1994 feb;10(1):37-40.
ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE Preparation Products And Raw materials
Tag:ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE(105565-55-7) Related Product Information
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