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Pranoprofen

Pranoprofen Suppliers list
Company Name: Hebei Chuanghai Biotechnology Co., Ltd
Tel: +8615531157085
Email: abby@chuanghaibio.com
Products Intro: Product Name:Pranoprofen
CAS:52549-17-4
Purity:99% Package:1kg;10.00;USD
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-29-81139210 +86-18192627656
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Products Intro: Product Name:Pranoprofen
CAS:52549-17-4
Purity:99% Package:1KG;1USD|25KG;11USD|100KG;22USD
Company Name: Hebei Mujin Biotechnology Co.,Ltd
Tel: +86 13288715578 +8613288715578
Email: sales@hbmojin.com
Products Intro: Product Name:Pranoprofen
CAS:52549-17-4
Purity:99% Package:25KG
Company Name: Hebei Chuanghai Biotechnology Co,.LTD
Tel: +86-13131129325
Email: sales1@chuanghaibio.com
Products Intro: Product Name:Pranoprofen
CAS:52549-17-4
Purity: 99% Package:1KG;1.90;USD
Company Name: airuikechemical co., ltd.
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Products Intro: Product Name:Pranoprofen
CAS:52549-17-4
Purity:99.9% Package:1g;0.00;USD|5g;0.00;USD|25g;0.00;USD

Pranoprofen manufacturers

  • Pranoprofen
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  • 2025-04-29
  • CAS:52549-17-4
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  • Purity: 97.99%
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  • Pranoprofen
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  • 2025-04-27
  • CAS:52549-17-4
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  • Purity: 97.99%
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  • Pranoprofen
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  • $10.00 / 1kg
  • 2025-04-23
  • CAS:52549-17-4
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 100 mt
Pranoprofen Basic information
Product Name:Pranoprofen
Synonyms:PRANOPROFEN;(RS)-Pranoprofen;5H-[1]Benzopyrano[2,3-b]pyridine-7-acetic acid, a-methyl- (9CI);a-Methyl-5H-[1]benzopyrano[2,3-b]pyridine-7-ylacetic acid;dl-Pranoprofen;Y 8004;pyranoprofen;(S)-2-[5H-[1]Benzopyrano[2,3-b]pyridin-7-yl]propionic acid
CAS:52549-17-4
MF:C15H13NO3
MW:255.27
EINECS:682-035-7
Product Categories:NIFLAN;>97%,BR;52549-17-4;Pharmaceuticals;Intermediates & Fine Chemicals;Heterocycles;Aromatics
Mol File:52549-17-4.mol
Pranoprofen Structure
Pranoprofen Chemical Properties
Melting point 182-183°
Boiling point 398.5°C (rough estimate)
density 1.1654 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka4.27±0.10(Predicted)
form powder
color white to beige
CAS DataBase Reference52549-17-4(CAS DataBase Reference)
Safety Information
RIDADR UN 2811 6.1 / PGIII
RTECS DJ3100950
ToxicityLD50 in male mice, rats (mg/kg): 447.3, 87.3 orally (Edanaga)
MSDS Information
Pranoprofen Usage And Synthesis
Chemical PropertiesOff-White Solid
OriginatorNiflan, Yoshitomi ,Japan ,1981
UsesPranoprofen is an anti-inflammatory used in ophthalmology.
DefinitionChEBI: Pranoprofen is a pyridochromene.
Manufacturing ProcessA mixture of 100 g of ethyl 2-cyano-2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionate, 500 ml of glacial acetic acid and 200 g of concentrated hydrochloric acid is refluxed for 48 hours. The reaction mixture is concentrated, and the residue is dissolved in hot water. The solution is adjusted to pH 2 to 3 by addition of 10% sodium hydroxide. The resulting crystalline precipitate is washed thoroughly with water, and recrystallized from aqueous dioxane to give 74 g of 2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionic acid as white crystals melting at 183°C to 183.5°C.
Therapeutic FunctionAnalgesic, Antiinflammatory
General DescriptionPranoprofen is an arylalkanoic acid and a non-steroidal anti-inflammatory drug.
Biochem/physiol ActionsPranoprofen is used in eyes to treat chronic allergic conjunctivitis. It is also used as an anti-inflammatory and analgesic drug after strabismus surgery.
Pranoprofen Preparation Products And Raw materials
Raw materialsHydrochloric acid
Tag:Pranoprofen(52549-17-4) Related Product Information
Centchroman Imidocarb dipropionate Folic acid Propionic acid Nandrolone phenylpropionate 3-(4-Hydroxyphenyl)propionic acid Ethyl 2-(Chlorosulfonyl)acetate 3-Phenylpropionic acid Ascoric Acid Ibuprofen N,N-dimethylcarbamoylmethyl alpha,2-dimethyl-5H-1-benzopyrano(2,3-b)pyridine-7-acetate ALFA-METHYL-5H-[1] BENZOPYRANO [2,3-B] PYRIDINE-7-ACETIC ACID ETHYL ESTER 4-METHOXY-3-METHYLPHENYLACETIC ACID Pranoprofen l-Pranoprofen,(S)-(+)-Pranoprofen (R)-Pranoprofen,(R)-(-)-Pranoprofen,d-Pranoprofen 2-(4-METHOXY-3-METHYLPHENYL)ACETALDEHYDE ALFA-METHYL-ALFA-CYANO-5H-[1] BENZOPYRANO [2,3-B] PYRIDINE-7-ACETIC ACID ETHYL ESTER

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