| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:FPL 64176;2,5-DiMethyl-4-[2-(phenylMethyl)benzoyl]-1H-pyrrole-3-carboxylicacidMethylester
CAS:120934-96-5
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| | FPL 64176 Basic information |
| Product Name: | FPL 64176 | | Synonyms: | FPL 64176;2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXLIC ACID METHYL ESTER;2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXYLIC ACID METHYL ESTER;2,5-Dimethyl-4-(2-benzylbenzoyl)-1H-pyrrole-3-carboxylic acid methyl ester;4-(2-Benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid methyl ester;FPL 64176 >94% POTENT CA2+ CHANNEL (;MDMWHKZANMNXTF-UHFFFAOYSA-N;ARC-64176 | | CAS: | 120934-96-5 | | MF: | C22H21NO3 | | MW: | 347.41 | | EINECS: | | | Product Categories: | Calcium channel | | Mol File: | 120934-96-5.mol |  |
| | FPL 64176 Chemical Properties |
| storage temp. | 2-8°C | | solubility | DMSO: 10 mg/mL Solutions should be freshly prepared. | | form | solid | | color | tan |
| | FPL 64176 Usage And Synthesis |
| Uses | FPL-64176 is a nondihydropyridine Ca2+ channel activator. | | Definition | ChEBI: FPL 64176 is 1H-Pyrrole substituted at C-2 and -5 by methyl groups, at C-3 by methoxycarbonyl and at C-4 by a 2-benzylbenzoyl group. It has a role as a calcium channel agonist. It is a member of pyrroles and a carboxylic ester. | | Biological Activity | Potent activator of L-type Ca 2+ channels (EC 50 = 16 nM). 40-fold more potent than Bay K 8644 (1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester ) as a positive inotrope in guinea pig atria. | | Biochem/physiol Actions | Potent Ca2+ channel (L-type) activator. | | storage | Store at RT |
| | FPL 64176 Preparation Products And Raw materials |
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