| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:Donitriptan hydrochloride;1-[[[3-(2-AMinoethyl)-1H-indol-5-yl]oxy]acetyl]-4-(4-cyanophenyl)-piperazinehydrochloride
CAS:170912-52-4
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
EMMX Biotechnology LLC
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| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:Donitriptan hydrochloride
CAS:170912-52-4
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| Company Name: |
Shanghai Han-Xiang Chemical Co., Ltd.
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| Tel: |
15971444841 |
| Email: |
amber@biochempartner.com |
| Products Intro: |
Product Name:Donitriptan
CAS:170912-52-4
Purity:98% HPLC LCMS Package:1KG;100KG
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| | DONITRIPTAN Basic information |
| Product Name: | DONITRIPTAN | | Synonyms: | DONITRIPTAN;1-[[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-4-(4-cyanophenyl)-piperazinehydrochloride;Donitriptan hydrochloride;DONITRIPTANUM;4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]piperazin-1-yl]benzonitrile;Benzonitrile, 4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]-1-piperazinyl]-;5-hydroxytryptamine Receptor,Donitriptan,Serotonin Receptor,Inhibitor,inhibit,5-HT Receptor | | CAS: | 170912-52-4 | | MF: | C23H25N5O2 | | MW: | 403.48 | | EINECS: | | | Product Categories: | | | Mol File: | 170912-52-4.mol |  |
| | DONITRIPTAN Chemical Properties |
| Boiling point | 727.1±60.0 °C(Predicted) | | density | 1.32±0.1 g/cm3(Predicted) | | storage temp. | Desiccate at RT | | solubility | Soluble in DMSO | | pka | 16.72±0.30(Predicted) | | form | Solid | | color | White to off-white |
| | DONITRIPTAN Usage And Synthesis |
| Uses | A novel 5-hydroxytryptamine (5-HT) derivative with potent, selective, and unique high intrinsic activity at 5-HT1B/1D receptors in models relevant to migraine. An antimigraine agent. | | Biological Activity | Brain penetrant 5-HT 1B/1D agonist (pK i values are 9.3 and 9.4 for 5-HT 1D and 5-HT 1B respectively). Inhibits capsaicin-induced external carotid vasodilation and produces selective carotid vasoconstriction in various animal species. Displays antimigraine activity. |
| | DONITRIPTAN Preparation Products And Raw materials |
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