2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE

2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE Suppliers list

Company Name:	Shenzhen Nexconn Pharmatechs Ltd
Tel:	+86-755-89396905 +86-15013857715
Email:	admin@nexconn.com
Products Intro:	Product Name:2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE CAS:265312-55-8 Purity:0.98 Package:1KG;10KG;50KG

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354 +1-00000000000
Email:	marketing@targetmol.com
Products Intro:	Product Name:Ryuvidine CAS:265312-55-8 Package:10 mg；25 mg；5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Aladdin Scientific
Tel:	+1-+1(833)-552-7181
Email:	sales@aladdinsci.com
Products Intro:	Product Name:Ryuvidine CAS:265312-55-8 Purity:>=98% Package:$33.9/1mg;$129.9/5mg;$199.9/10mg;$448.9/25mg;$809.9/50mg;Bulk package Remarks:98%

Company Name:	Tianjin shanhaijing medicine technology co., ltd Gold
Tel:	19129375004 15321929114
Email:	yangtzechem@163.com
Products Intro:	Product Name:Ryuvidine CAS:265312-55-8 Purity:99% HPLC Package:100mg;500mg;1g;5g;10g;472g

Company Name:	3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:	821-50328103-801 18930552037
Email:	3bsc@sina.com
Products Intro:	Product Name:Ryuvidine;2-Methyl-5-[(4-Methylphenyl)aMino]-4,7-benzothiazoledione CAS:265312-55-8 Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g

2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE Basic information

Product Name:	2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE
Synonyms:	2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE;RYUVIDINE;Cdk4 Inhibitor III;2-methyl-5-(4-methylanilino)-1,3-benzothiazole-4,7-dione;4,7-Benzothiazoledione, 2-methyl-5-[(4-methylphenyl)amino]-;2-methyl-5-[(4-methylphenyl)amino]benzothiazole-4,7-dione
CAS:	265312-55-8
MF:	C15H12N2O2S
MW:	284.33
EINECS:
Product Categories:
Mol File:	265312-55-8.mol

2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE Chemical Properties

Boiling point	463.8±45.0 °C(Predicted)
density	1.416±0.06 g/cm3(Predicted)
storage temp.	Store at +4°C
solubility	Soluble to 20 mM in DMSO and to 5 mM in ethanol
form	Black-purple solid
pka	-1.63±0.20(Predicted)
color	Brown to black

Safety Information

MSDS Information

2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE Usage And Synthesis

Uses	Ryuvidine is an antifungal agent used against pathogenic fungi.
Definition	ChEBI: 2-methyl-5-(4-methylanilino)-1,3-benzothiazole-4,7-dione is an aminotoluene.
General Description	A cell-permeable dioxobenzothiazole compound that acts a selective Cdk4 inhibitor (IC₅₀ = 6.0 μM for Cdk4/D1 and >200 μM for Cdk2/A). Exhibit better cytotoxic potential against cancer cells (IC₅₀ = 0.61, 1.08, 0.30, and 1.21 μg/ml against A 549, Col 1, HL-60, and HepG2 tumor cells, respectively) than Cisplatin (Cat. No. 232120).
Biological Activity	Cyclin-dependent kinase (cdk) 4 inhibitor (IC 50 = 6.0 μ M at cdk4/cyclin D1) that displays > 33-fold selectivity over cdk2 (IC 50 > 200 μ M at cdk2/cyclin A). Cytotoxic against a range of human cancer cells (IC 50 values are 0.30, 0.61, 1.08 and 1.21 μ g/mL for HL-60, A549, Col 1 and HepG2 cells respectively).
Biochem/physiol Actions	Cell permeable: yes
storage	Store at +4°C

2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE Preparation Products And Raw materials

Tag:2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE(265312-55-8) Related Product Information

1-(2-METHYL-1,3-THIAZOL-4-YL)ETHANONE 4,5-THIAZOLEDICARBOXALDEHYDE 2-METHYL-5-[(4-METHYLPHENYL)AMINO]-4,7-BENZOTHIAZOLEDIONE

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