- DIISOPROPYLCHLOROSILANE
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- $0.00 / 1KG
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2024-09-09
- CAS:2227-29-4
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1000KG /month
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| Diisopropylchlorosilane Basic information |
| Diisopropylchlorosilane Chemical Properties |
Boiling point | 58-60 °C50 mm Hg(lit.) | density | 0.883 g/mL at 25 °C(lit.) | refractive index | n20/D 1.429(lit.) | Fp | 72 °F | storage temp. | Inert atmosphere,Room Temperature | solubility | generally sol organic solvents; reacts with alcohols,
ammonia,and water. | form | clear liquid | color | Colorless to Almost colorless | Specific Gravity | 0.883 | Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents | BRN | 2231355 | InChI | InChI=1S/C6H15ClSi/c1-5(2)8(7)6(3)4/h5-6,8H,1-4H3 | InChIKey | CGXYLRTYLIHXEE-UHFFFAOYSA-N | SMILES | [SiH](Cl)(C(C)C)C(C)C | CAS DataBase Reference | 2227-29-4(CAS DataBase Reference) | EPA Substance Registry System | Silane, chlorobis(1-methylethyl)- (2227-29-4) |
Hazard Codes | C | Risk Statements | 10-34 | Safety Statements | 26-36/37/39-45 | RIDADR | UN 2986 8/PG 2 | WGK Germany | 3 | F | 10-21 | TSCA | Yes | HazardClass | 3.1 | PackingGroup | II | HS Code | 29319090 |
| Diisopropylchlorosilane Usage And Synthesis |
Physical properties | bp 150–153°C,bp 54–55°C/45 mmHg;
d 0.872 gmL?1 | Uses | Intramolecular
hydrosilylation is also possible within β-diisopropylsilyloxy
esters (13), constituting an exceptionally mild method for reducing
ester groups to the aldehyde oxidation level (eq 4).The derivatives
(13) may be synthesized from β-hydroxy esters (12) as described
above for the analogous ketones. Treatment with fluoride
ions (but not Lewis acids) induces hydride transfer to give
alkoxysiladioxanes (14) in excellent yields (≥95%). Although
usually performed in dichloromethane, the hydrosilylation may
also be accomplished with ethyl acetate as solvent, providing
strong evidence for intramolecularity.![Reactions of DIISOPROPYLCHLOROSILANE Reactions of DIISOPROPYLCHLOROSILANE](https://www.chemicalbook.com/NewsImg/2021-08-31/20210831650008881457567227.jpg) | Application | Used in a silylation-reduction-allylation sequence of
β-hydroxy esters to homoallylic-substituted 1,3-diols.
Used in the silylation-hydrosilation-oxidation of allyl
alcohols to 1,3-diols. Reaction carried out in
diastereoselective manner. Reduces β-hydroxy ketones to
anti-1,3 diols. | Preparation | obtained by reaction of trichlorosilane with
isopropylmagnesium chloride;the original yield of 45% may
be raised to 70–80% by employing conc hydrochloric acid to
quench the reaction. | Purification Methods | Impurities can be readily detected by 1H NMR. Purify it by fractional distillation [Gilman & Clark J Am Chem Soc 69 1499 1947, Allen et al. J Chem Soc 3668 1957]. |
| Diisopropylchlorosilane Preparation Products And Raw materials |
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