Log in | Join Free | china | japan | germany

VU 0357017 hydrochloride

Request For Quotation
VU 0357017 hydrochloride Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:VU0357017
CAS:1135242-13-5
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:VU 0357017 hydrochloride
CAS:1135242-13-5
Purity:>98% Package:100mg Remarks:BOC Sciences also provides custom synthesis services for VU 0357017 hydrochloride.
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695
Email: laboratory@coreychem.com
Products Intro: Product Name:VU 0357017 hydrochloride
CAS:1135242-13-5
Purity:95.0% windy 308
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:VU0357017 HCI
CAS:1135242-13-5
Purity:98% Package:5mg Remarks:V3036
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:VU0357017 hydrochloride；ML071 hydrochloride;CID-25010775;VU 0357017 hydrochloride
CAS:1135242-13-5
Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
VU 0357017 hydrochloride Basic information
Product Name:VU 0357017 hydrochloride
Synonyms:VU 0357017 hydrochloride;4-[[2-[(2-Methylbenzoyl)aMino]ethyl]aMino]-1-piperidinecarboxylic Acid Ethyl Ester Hydrochloride;4-[[2-[(2-Methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid ethyl ester monohydrochloride;CID 25010775;Ethyl 4-(2-(2-methylbenzamido)ethylamino)piperidine-1-carboxylate hydrochloride;ML071 hydrochloride;SID 56353039;VU0357017 monohydrochloride
CAS:1135242-13-5
MF:C18H28ClN3O3
MW:369.9
EINECS:
Product Categories:Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Positive allosteric modulator of muscarinic M1 receptors.;Amines
Mol File:1135242-13-5.mol
VU 0357017 hydrochloride Structure
VU 0357017 hydrochloride Chemical Properties
storage temp. Inert atmosphere,2-8°C
solubility DMSO: ≥10mg/mL
form powder
color white to off-white
Safety Information
Hazard Codes N
Risk Statements 52/53
Safety Statements 61
WGK Germany 2
MSDS Information
VU 0357017 hydrochloride Usage And Synthesis
UsesVU0357017 is a subtype-selective M1 muscarinic acetylcholine allosteric agonist. VU0357017 has a potency of 200 nM and Achmax of 81% and had no activity at M2-M5 up to the highest concentrations tested and also had little or no detectable antagonist activity at any other mAChR subtype at concentrations over 2 orders of magnitude higher than those required to activate M1 or activity at a large panel of GPCRs, ion channels, and transporters. In contrast, TBPB inhibited responses to ACh at each of the other mAChR subtypes. VU0357017 was active in reversing cognitive deficits induced by Scopolamine (S200000) in a preclinical rodent model.
UsesVU 0357017 Hydrochloride is a cholinergic M1 receptor antagonist and a cholinomimetic agent used for the treatment of behavioral and/or mental disorders.
storage+4°C
VU 0357017 hydrochloride Preparation Products And Raw materials
Tag:VU 0357017 hydrochloride(1135242-13-5) Related Product Information
N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide VU 0285683 VU0155041 VU0134992(hydrochloride) VU6005649 VU 591 hydrochloride VU0810464 VU0483605 N-(4-Chloro-3-methoxyphenyl)-2-pyridinecarboxamide 1-(4-Methoxybenzyl)-5-trifluoromethoxyisatin VU 6008667 (1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide 5-Amino-3,4-dimethyl-thieno[2,3-c]pyridazine-6-carboxylic acid 4-trifluoromethanesulfonyl-benzylamide 3-methylsulfanyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine VU 0360172 VU 0365114 VU 0357121 VU 0360223