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| Product Name: | SQ 109 | | Synonyms: | SQ 109;NSC 722041;N-[(2E)-3,7-Dimethyl-2,6-octadienyl]-N'-tricyclo[3.3.1.1(3,7)]dec-2-yl-1,2-ethanediamine;Cenobamate;N'-(2-adamantyl)-N-[(2E)-3,7-dimethylocta-2,6-dienyl]ethane-1,2-diamine;SQ 109; SQ-109; NSC 722041;1,2-Ethanediamine, N1-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-N2-tricyclo[3.3.1.13,7]dec-2-yl-;SQ109 >=98% (HPLC) | | CAS: | 502487-67-4 | | MF: | C22H38N2 | | MW: | 330.55 | | EINECS: | | | Product Categories: | | | Mol File: | 502487-67-4.mol |  |
| | SQ 109 Chemical Properties |
| Boiling point | 450.0±33.0 °C(Predicted) | | density | 0.97±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly) | | pka | 9.80±0.20(Predicted) | | form | oil | | color | colorless to yellow |
| | SQ 109 Usage And Synthesis |
| Uses | SQ109 has been used:
- as an antitubercular?agent to study its interactions with mycobacterial membrane proteins large 3 (MmpL3) binding pocket
- as a positive control to determine the minimum inhibitory concentration (MIC) of ohmyungsamycins (OMS) A and B against Mycobacterium tuberculosis?(Mtb) using the resazurin microtiter assay (REMA) plate method
- as an inhibitor of MmpL3 to explore the utility of mycobacterial CRISPR interference for validating target gene essentiality and compound mode of action
| | General Description | SQ109 is a 1,2-ethylenediamine, which is related to ethambutol. | | Biochem/physiol Actions | SQ109 exhibits activity against Helicobacter pylori and the fungi Candida albicans. It might also possess anti-bacterial activity. | | target | Mycobacterium |
| | SQ 109 Preparation Products And Raw materials |
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