|
| (chlorodifluoroMethyl)triMethylsilane Basic information |
| (chlorodifluoroMethyl)triMethylsilane Chemical Properties |
Boiling point | 90.0±40.0 °C(Predicted) | density | 1.039±0.06 g/cm3(Predicted) | form | liquid | color | colorless |
Risk Statements | 11 | Safety Statements | 24/25 | TSCA | No | HS Code | 29319090 |
| (chlorodifluoroMethyl)triMethylsilane Usage And Synthesis |
Uses | (Chlorodifluoromethyl)trimethylsilane, is one of the partially fluorinated compounds, which are often used for diverse applications in materials science, agrochemistry, and the pharmaceutical industry. | Uses | (chlorodifluoroMethyl)triMethylsilane,also known as Hu reagent,it can be used to generate difluorocarbene at higher temperatures catalyzed by chloride ion. | Reactions |
(1) Difluoromethylenation of alkenes.
![正在上传...](/NewsImg/2024-01-19/6384127656980869938917628.png) Refs. 1) Angew. Chem. Int. Ed. 2011, 50, 7153 –7157; 2) Chem. Commun. 2011, 47, 2411–2413. (2) Difluoromethylenation of alkynes.
![正在上传...](/NewsImg/2024-01-19/6384127638969139722391130.png) Refs. 1) Angew. Chem. Int. Ed. 2011, 50, 7153 –7157; 2) Chem. Commun. 2011, 47, 2411–2413. (3) Difluoromethylenation of TMSCN.
![Difluoromethylenation of TMSCN Difluoromethylenation of TMSCN](/NewsImg/2024-01-19/6384127613923207171295231.png) Ref. J. Org. Chem. 2012, 77, 5850?5855. (4) Difluoromethylenation of benzyl and alkylzinc halides.
![Difluoromethylenation of benzyl and alkylzinc halides Difluoromethylenation of benzyl and alkylzinc halides](/NewsImg/2024-01-19/6384127616425050273903719.png) Ref. Org. Lett. 2013, 15, 917 – 919. (5) Fluorination aminocarbonylation of aldehydes
![(chlorodifluoroMethyl)triMethylsilane (chlorodifluoroMethyl)triMethylsilane](/NewsImg/2024-01-19/6384127619499326118705765.png) Ref. Angew. Chem. Int. Ed. 2022, e202115467
| References |
[1]Angewandte Chemie International Edition.DOI :10.1002/anie.202283811 [2]The Journal of Organic Chemistry.DOI :10.1021/acs.orglett.2c02899
|
| (chlorodifluoroMethyl)triMethylsilane Preparation Products And Raw materials |
|