- GSK-LSD1
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- $30.00 / 1mg
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2024-11-19
- CAS:1431368-48-7
- Min. Order:
- Purity: 99.59%
- Supply Ability: 10g
- GSK-LSD1
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- $0.00 / 1KG
-
2022-09-08
- CAS:1431368-48-7
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1ton
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| | GSK-LSD1 Basic information |
| Product Name: | GSK-LSD1 | | Synonyms: | rel-N-[(1R,2S)-2-Phenylcyclopropyl]-4-piperidinamine;GSK-LSD1 2hydrochloride;GSK-LSD1 dihydrochloride;GSK-LSD1(LSD1inhibitor);N-((1R,2S)-2-phenylcyclopropyl)piperidin-4-amine dihydrochloride;GSK-LSD1 (trans-racemic) dihydrochloride;rel- N-[(1R,2S)-2-Phenylcyclopropyl]-4-Piperidinamine hydrochloride (1:2);GSK-LSD | | CAS: | 1431368-48-7 | | MF: | C14H20N2 | | MW: | 216.32 | | EINECS: | | | Product Categories: | Inhibitors | | Mol File: | 1431368-48-7.mol |  |
| | GSK-LSD1 Chemical Properties |
| Boiling point | 347.4±42.0 °C(Predicted) | | density | 1.07±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | H2O: soluble20mg/mL, clear | | form | powder | | pka | 10.14±0.10(Predicted) | | color | white to beige |
| | GSK-LSD1 Usage And Synthesis |
| Uses | GSK LSD1 Dihydrochloride is an irreversible mechanism-based inhibitor of LSD1. Lysine-specific demthylase 1 (LSD1) belonges to the flavin adenine dinucleotide (FAD) family-dependant amine oxidases that include MAOs and PAOs. Inhibits cell proliferation in cancer cell lines. | | Uses | GSK-LSD1 has been used as a lysine specific demethylase 1 (LSD1) inhibitor in mice to study sepsis-induced mortality. It has also been used as an inhibitor to study if the effect of phenelzine activation of human immunodeficiency virus (HIV) latency is caused due to LSD1. | | Biochem/physiol Actions | GSK-LSD1 is a potent and selective inhibitor of lysine specific demethylase 1 (LSD1). GSK-LSD1 potently inhibits proliferation of varies cancer cell lines by changing gene expression patterns. For full characterization details, please visit the GSK-LSD1 probe summary on the Structural Genomics Consortium (SGC) website.To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc | | references | [1]. structural genomics consortium.http://www. thesgc.org/chemical-probes/lsd1. |
| | GSK-LSD1 Preparation Products And Raw materials |
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