- Buserelin acetate
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- $40.00 / 1kg
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2024-10-25
- CAS:68630-75-1
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 10 tons
- BUSERELIN
-
- $70.00 / 1kg
-
2024-08-27
- CAS:68630-75-1
- Min. Order: 10kg
- Purity: 0.99
- Supply Ability: 20tons
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| | BUSERELIN Basic information |
| Product Name: | BUSERELIN | | Synonyms: | 6-(o-(1,1-dimethylethyl)-d-serine)-luteinizinghormone-releasingfactor(pig;9-(n-ethyl-l-prolinamide)-10-deglycinamide,monoacetate(salt);buserelinacetate;hoe766;hoe766mp;PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-NHET;P-GLU-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-NHET;pGlu-His-Trp-Ser-Tyr-D-Ser(t-Bu)-Leu-Arg-Pro-NHEt, des-Gly10-[D-Ser[t-Bu]6]-LH-RH ethylamide | | CAS: | 68630-75-1 | | MF: | C62H90N16O15 | | MW: | 1299.5 | | EINECS: | 636-185-5 | | Product Categories: | Amino Acids & Derivatives;Intermediates & Fine Chemicals;Peptides;Pharmaceuticals | | Mol File: | 68630-75-1.mol |  |
| | BUSERELIN Chemical Properties |
| Melting point | 186-188°C | | storage temp. | -20°C | | solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) | | form | Solid | | color | White to Off-White | | Stability: | Hygroscopic |
| | BUSERELIN Usage And Synthesis |
| Description | Buserelin acetate is a potent analog of the hypothalamic hormone, luteinizing
hormone-releasing hormone (LH-RH). Chronic administration of higher doses of
buserelin desensitizes the pituitary, resulting in a decreased production of
luteinizing hormone (LH), follicle stimulating hormone (FSH), and eventually
sex steroids (testosterone in males and estradiol in females). Initial approval is
for use in achieving medical castration in the treatment of advanced prostate
cancer. It has also been investigated for the treatment of endometriosis,
leiomyoma, precocious puberty, advanced breast cancer and infertility. | | Chemical Properties | White Solid | | Originator | Hoechst AG (W. Germany) | | Uses | Gondadotropin-releasing hormone agonist, used to treat hormone-responsive cancers such as prostate and breast cancer. Synthetic nonapeptide agonist analog of LH-RH. Antineolpastic (hormonal). | | Definition | ChEBI: Buserelin acetate is an organic molecular entity. | | Brand name | Suprefact
(Hoechst-Roussel). | | Biochem/physiol Actions | Buserelin is an LH-RH agonist. |
| | BUSERELIN Preparation Products And Raw materials |
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