盐酸异黄连碱
| 中文名称 | 盐酸异黄连碱 |
|---|---|
| 中文同义词 | 盐酸异黄连碱 |
| 英文名称 | Pseudocoptisine chloride |
| 英文同义词 | Pseudocoptisine chloride;Isocoptisine chloride;Isocoptisine,anti-amnestic,Pseudocoptisine chloride,cytokines,anti-inflammatory,Pseudocoptisine,pro-inflammatory,RAW 264.7,Cholinesterase (ChE),inhibit,Inhibitor |
| CAS号 | 30044-78-1 |
| 分子式 | C19H14ClNO4 |
| 分子量 | 355.77 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 30044-78-1.mol |
| 结构式 |  |
盐酸异黄连碱 性质
| 储存条件 | Store at -20°C |
|---|---|
| 形态 | 固体 |
| 颜色 | 黄至棕色 |
Pseudocoptisine (0, 60, 90 μM; 1 hour) dose-dependently inhibited LPS-induced NO production in RAW264.7 cells.
Pseudocoptisine (30-90 μM; 1 hour; RAW264.7 cells) significantly reduces the LPS-induced TNF-α and IL-6 production and their mRNA expressions.
Pseudocoptisine acetate reduces levels of the pro-inflammatory mediators, such as, iNOS, COX-2, TNF-alpha, and IL-6 through the inhibition of NF-kappaB activation via the suppression of ERK and p38 phosphorylation in RAW 264.7 cells.
The anti-amnesic activities of Pseudocoptisine in mice on the learning and memory impairments induced by scopolamine (1.0 mg/kg, i.p.) are examined. Pseudocoptisine (2.0 mg/kg, p.o.) significantly reverses cognitive impairments in mice by passive avoidance test.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024/04/30 | HY-N6894A | Pseudocoptisine chloride | 1 mg | 800元 | |
| 2024/04/30 | HY-N6894A | 盐酸异黄连碱 Pseudocoptisine chloride | 30044-78-1 | 5mg | 2000元 |