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| (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Basic information |
| (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Chemical Properties |
storage temp. | Desiccate at RT | solubility | Soluble to 10 mM in ethanol and to 100 mM in DMSO | form | Powder | color | White to yellow |
| (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Usage And Synthesis |
Uses | This molecule inhibits MDMX expression in breast cancer cells through activating p53 resulting in apoptosis in cancer cells. | Biological Activity | Cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay. |
| (10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE Preparation Products And Raw materials |
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