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| | 5-Chloro-6-hydroxynicotinic Acid Basic information | | Structure |
| | 5-Chloro-6-hydroxynicotinic Acid Chemical Properties |
| Melting point | ≥300 °C(lit.) | | Boiling point | 334.6±42.0 °C(Predicted) | | density | 1.4914 (rough estimate) | | refractive index | 1.5810 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | form | powder to crystal | | pka | 3.38±0.50(Predicted) | | color | White to Light yellow to Light orange | | CAS DataBase Reference | 54127-63-8(CAS DataBase Reference) |
| | 5-Chloro-6-hydroxynicotinic Acid Usage And Synthesis |
| Structure | 5-Chloro-6-hydroxynicotinic Acid （5Cl6HNA) was recrystallized four times from ethanol at 345 K. The obtained white crystalline solid was first dried in a vacuum at 1.3 Pa and 353 K. The crystals were then ground with a mortar and a pestle and further dried for 24 h at 1.3 Pa and 353 K. The powder pattern obtained at 295 ± 1 K was indexed as monoclinic, space group P21/c, with a= 5.478 Å, b= 10.545 Å, c= 11.796 Å, β=97.76°. These results are in agreement with those obtained in this work from single crystal X-ray diffraction experiments carried out at 293 ±2K(P21/c, a ) 5.469 Å, b = 10.529 Å, c= 11.795 Å, β= 97.72°). DSC (fusion, β= 2 K ·min-1 ): Ton= 582.2 K and Tmax= 585.6 K[1].
 | | Chemical Properties | white to beige fine crystalline powder | | References | [1] Rui C. Santos. “Energetics and Structure of Hydroxynicotinic Acids. Crystal Structures of 2-, 4-, 6-Hydroxynicotinic and 5-Chloro-6-hydroxynicotinic Acids.” The Journal of Physical Chemistry B 113 43 (2009): 14291–14309.
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| | 5-Chloro-6-hydroxynicotinic Acid Preparation Products And Raw materials |
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