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| | 3-ETHYL-3-METHYLGLUTARIMIDE Basic information |
| Product Name: | 3-ETHYL-3-METHYLGLUTARIMIDE | | Synonyms: | 2,6-Piperidinedione, 4-ethyl-4-methyl-;3,3-Methylethylilotarimide;2,6-DIOXO-4-METHYL-4-ETHYLPIPERIDINE;BEMEGRIDE, 99+%;4-Ethyl-4-methylpiperidine -2,6-dione;β,β-Methylethylglutarimide;NP-13;EUKRATON | | CAS: | 64-65-3 | | MF: | C8H13NO2 | | MW: | 155.19 | | EINECS: | 200-588-0 | | Product Categories: | | | Mol File: | 64-65-3.mol |  |
| | 3-ETHYL-3-METHYLGLUTARIMIDE Chemical Properties |
| Melting point | 126-127 °C(lit.) | | Boiling point | 279°C (rough estimate) | | density | 1.1174 (rough estimate) | | refractive index | 1.4860 (estimate) | | storage temp. | Sealed in dry,2-8°C | | Water Solubility | Soluble in water | | solubility | DMSO:31.0(Max Conc. mg/mL);199.76(Max Conc. mM)
Ethanol:31.0(Max Conc. mg/mL);199.76(Max Conc. mM) | | form | powder | | pka | pKa 11.7 (Uncertain) | | color | white | | Merck | 14,1027 | | CAS DataBase Reference | 64-65-3(CAS DataBase Reference) | | EPA Substance Registry System | Bemegride (64-65-3) |
| Hazard Codes | T | | Risk Statements | 23/24/25 | | Safety Statements | 22-36/37/39-45 | | RIDADR | UN 2811 6.1/PG 2 | | WGK Germany | 3 | | RTECS | MA4550000 | | HazardClass | 6.1(a) | | PackingGroup | II | | HS Code | 2933399990 | | Toxicity | LD50 in male mice (mg/kg): 20.1 ±1.41 i.v., 43.0 ±1.8 s.c.; LD50 in male rats (mg/kg): 16.3 ±1.24 i.v., 23.5 ±1.67 i.p (Hahn, Oberdorf) |
| | 3-ETHYL-3-METHYLGLUTARIMIDE Usage And Synthesis |
| Chemical Properties | white to off-white flakes or powder | | Uses | CNS stimulant;GABA antagonist | | Definition | ChEBI: 4-ethyl-4-methylpiperidine-2,6-dione is a member of piperidones. | | Brand name | Megimide
(Abbott). | | General Description | White crystalline solid. Sublimes at 212°F and 200 mm pressure. | | Air & Water Reactions | Insoluble in water. | | Reactivity Profile | 3-ETHYL-3-METHYLGLUTARIMIDE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). | | Health Hazard | ACUTE/CHRONIC HAZARDS: When heated to decomposition it emits toxic fumes. | | Fire Hazard | Flash point data for 3-ETHYL-3-METHYLGLUTARIMIDE are not available. 3-ETHYL-3-METHYLGLUTARIMIDE is probably not flammable. | | Safety Profile | Poison by ingestion,
intravenous, intraperitoneal, intramuscular,
subcutaneous, and parented routes. Human
systemic effects by ingestion: wakefulness,
hallucinations, distorted perceptions, toxic
psychosis. An analeptic, central nervous
system stimulant; used to counteract
barbiturate poisoning. When heated to
decomposition it emits toxic fumes of NOx. |
| | 3-ETHYL-3-METHYLGLUTARIMIDE Preparation Products And Raw materials |
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